Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TMIE [plasma membrane]
Stable Identifier
R-HSA-9658863
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Transmembrane inner ear expressed protein, TMIE_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
TMIE [plasma membrane] (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (IHC) [plasma membrane] (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
TMIE [plasma membrane] (Homo sapiens)
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
TMIE [plasma membrane] (Homo sapiens)
MET channel:Tip link:USH1C:USH1G:MYO7A:cytoskeleton (OHC) [plasma membrane] (Homo sapiens)
MET channel [plasma membrane] (Homo sapiens)
TMIE [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NEW7 TMIE
Gene Names
TMIE
Chain
signal peptide:1-27, chain:28-156
Reference Genes
BioGPS Gene:259236 TMIE
COSMIC (genes):TMIE TMIE
CTD Gene:259236 TMIE
dbSNP Gene:259236 TMIE
ENSEMBL:ENSG00000181585 TMIE
HGNC:30800 TMIE
Monarch:259236 TMIE
NCBI Gene:259236 TMIE
OMIM:607237 TMIE
UCSC:Q8NEW7 TMIE
Reference Transcript
RefSeq:NM_147196.2 TMIE
Other Identifiers
11736711_at
11736712_at
1553600_PM_at
1553600_at
1553601_PM_a_at
1553601_a_at
16940233
259236
2620986
2620987
2620988
2620989
2620990
2620991
2620992
2620993
2620994
2620995
67459_at
8079426
A_14_P139243
A_24_P234462
A_33_P3261408
GE803871
GO:0007605
GO:0016020
GO:0042472
GO:0050877
HMNXSV003008535
HMNXSV003033670
Hs2.185777.1.A1_3p_at
ILMN_1726745
TC03000261.hg
Participates
as a component of
MET channel [plasma membrane] (Homo sapiens)
Cross References
ENSEMBL
ENSP00000494576
,
ENST00000643606
OpenTargets
ENSG00000181585
HPA
ENSG00000181585-TMIE
PRO
Q8NEW7
Pharos - Targets
Q8NEW7
GlyGen
Q8NEW7
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text