OGG1 S326C [nucleoplasm]

Stable Identifier
R-HSA-9658769
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
OGG1 Ser326Cys
OGG1 S326C [nucleoplasm] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
15073047 Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo

Aoki, K, Ito, K, Nojima, Y, Sunaga, N, Yokota, J, Kohno, T, Murakami, H, Yoshimura, K, Yamane, A

Carcinogenesis 2004
21376741 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes

Tudek, B, Cieśla, JM, Speina, E, Janik, J, Gackowski, D, Swoboda, M, Janowska, B, Olinski, R, Kowalewski, J

Mutat. Res. 2011
22451681 Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1

Hodges, NJ, Kershaw, RM

Mutagenesis 2012
24632493 hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide

Radicella, JP, Hall, J, Pauly, K, Epe, B, Bravard, A, Moritz, E

Carcinogenesis 2014
10497264 Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations

Radicella, JP, Boiteux, S, Dizdaroglu, M, Dherin, C

Nucleic Acids Res. 1999
26089588 OGG1 Mutations and Risk of Female Breast Cancer: Meta-Analysis and Experimental Data

Ali, K, Kayani, MA, Mehmood, H, Mahjabeen, I, Sabir, M

Dis. Markers 2015
11459633 DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326

Schlink, K, Götte, W, Hippler, B, Janssen, K, Oesch, F, Kaina, B

Mutat. Res. 2001
External Reference Information
External Reference
Gene Names
OGG1, MMH, MUTM, OGH1
Chain
chain:1-345
Other Identifiers
0002060524
0004810403
11727607_a_at
11727608_x_at
11727696_x_at
11740749_a_at
16937329
205301_s_at
205760_s_at
2609907
2609908
2609909
2609910
2609913
2609914
2609916
2609917
2609918
2609920
2609921
2609922
2609923
2609924
2609925
2609926
2609927
2609929
2609930
2609931
34146_at
34147_g_at
38333_at
38334_g_at
38335_at
4968
8077635
AB000410_s_at
A_14_P200082
A_23_P212196
A_23_P344392
A_24_P414183
GE58739
GO:0002526
GO:0003674
GO:0003677
GO:0003684
GO:0003824
GO:0004518
GO:0004519
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005759
GO:0005829
GO:0006259
GO:0006281
GO:0006284
GO:0006285
GO:0006287
GO:0006289
GO:0006355
GO:0006950
GO:0006974
GO:0006979
GO:0007568
GO:0008017
GO:0008092
GO:0008150
GO:0008152
GO:0008219
GO:0008534
GO:0009056
GO:0009058
GO:0009314
GO:0009416
GO:0016363
GO:0016607
GO:0016787
GO:0016798
GO:0016829
GO:0019104
GO:0032355
GO:0032357
GO:0032991
GO:0033683
GO:0034039
GO:0034641
GO:0034655
GO:0042493
GO:0043066
GO:0043226
GO:0044281
GO:0045007
GO:0045008
GO:0045471
GO:0051593
GO:0071276
GO:0140078
GO:1901291
HMNXSV003027366
HMNXSV003040435
HMNXSV003055999
ILMN_1706652
ILMN_1808340
ILMN_2352609
PH_hs_0024314
TC03000042.hg
TC03002210.hg
g8670531_3p_a_at
g8670533_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
L-serine 326 replaced with L-cysteine
Coordinate
326
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-cysteine.
A protein modification that effectively removes or replaces an L-serine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
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