OGG1 S326C [nucleoplasm]

Stable Identifier
R-HSA-9658769
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
OGG1 Ser326Cys
OGG1 S326C [nucleoplasm] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
26089588 OGG1 Mutations and Risk of Female Breast Cancer: Meta-Analysis and Experimental Data

Ali, K, Kayani, MA, Mehmood, H, Mahjabeen, I, Sabir, M

Dis. Markers 2015
15073047 Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo

Aoki, K, Ito, K, Nojima, Y, Sunaga, N, Yokota, J, Kohno, T, Murakami, H, Yoshimura, K, Yamane, A

Carcinogenesis 2004
11459633 DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326

Schlink, K, Götte, W, Hippler, B, Janssen, K, Oesch, F, Kaina, B

Mutat. Res. 2001
21376741 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes

Tudek, B, Cieśla, JM, Speina, E, Janik, J, Gackowski, D, Swoboda, M, Janowska, B, Olinski, R, Kowalewski, J

Mutat. Res. 2011
24632493 hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide

Radicella, JP, Hall, J, Pauly, K, Epe, B, Bravard, A, Moritz, E

Carcinogenesis 2014
22451681 Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1

Hodges, NJ, Kershaw, RM

Mutagenesis 2012
10497264 Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations

Radicella, JP, Boiteux, S, Dizdaroglu, M, Dherin, C

Nucleic Acids Res. 1999
Participates
Other forms of this molecule
Modified Residues
Name
L-serine 326 replaced with L-cysteine
Coordinate
326
PsiMod
A protein modification that effectively removes or replaces an L-serine.
A protein modification that effectively converts a source amino acid residue to an L-cysteine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cite Us!