OGG1 R131Q [nucleoplasm]

Stable Identifier
R-HSA-9658752
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
OGG1 Arg131Gln
OGG1 R131Q [nucleoplasm] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
19537786 The R46Q, R131Q and R154H polymorphs of human DNA glycosylase/beta-lyase hOgg1 severely distort the active site and DNA recognition site but do not cause unfolding

Anderson, PC, Daggett, V

J. Am. Chem. Soc. 2009
9662341 Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours

Chevillard, S, Oudard, S, Poupon, MF, Radicella, JP, Levalois, C, Dutrillaux, B, Boiteux, S, Lebeau, J

Oncogene 1998
10706276 Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

Bruner, SD, Verdine, GL, Norman, DP

Nature 2000
Participates
Other forms of this molecule
Modified Residues
Name
L-arginine 131 replaced with L-glutamine
Coordinate
131
PsiMod
A protein modification that effectively removes or replaces an L-arginine.
A protein modification that effectively converts a source amino acid residue to an L-glutamine.
Disease
Name Identifier Synonyms
lung cancer DOID:1324
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cite Us!