Reactome | S-GGC MRAS [plasma membrane]

S-GGC MRAS [plasma membrane]

Stable Identifier

R-HSA-9658449

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ras-related protein M-Ras, RASM_HUMAN

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O14807 MRAS

Gene Names

MRAS, RRAS3

Chain

chain:1-205, propeptide:206-208

Reference Genes

BioGPS Gene:22808 MRAS

COSMIC (genes):MRAS MRAS

CTD Gene:22808 MRAS

dbSNP Gene:22808 MRAS

ENSEMBL:ENSG00000158186 MRAS

ENSEMBL_homo_sapiens_GENE:ENSG00000158186.13 MRAS

HGNC:7227 MRAS

KEGG Gene (Homo sapiens):22808 MRAS

Monarch:22808 MRAS

NCBI Gene:22808 MRAS

OMIM:608435 MRAS

UCSC:O14807 MRAS

Reference Transcript

Other Identifiers

11716971_a_at

11758360_s_at

11758561_s_at

16946159

206538_PM_at

206538_at

225185_PM_at

225185_at

22808

2644566

2644567

2644568

2644569

2644571

2644589

2644603

2644604

2644610

2644611

2644612

2644613

2644614

2644615

2644616

2644617

38540_at

57217_at

8082965

A_14_P112094

A_14_P112544

A_14_P131120

A_23_P377197

A_24_P88850

GE54384

GO:0000166

GO:0003824

GO:0003924

GO:0003925

GO:0005515

GO:0005525

GO:0005886

GO:0007010

GO:0007165

GO:0007265

GO:0016020

GO:0016787

GO:0019003

GO:0023052

GO:0030036

GO:0030742

GO:0098772

GO:1990830

HMNXSV003047674

Hs.7298.1.A1_3p_at

ILMN_1748881

PH_hs_0016853

TC03000744.hg

Participates

as a component of

S-GCC MRAS:GTP [plasma membrane] (Homo sapiens)

Other forms of this molecule

S-GGC MRAS G23R [plasma membrane]

S-GGC MRAS G23V [plasma membrane]

S-GGC MRAS T68I [plasma membrane]

S-GGC MRAS G23D [plasma membrane]

Inferred To

mrasa [plasma membrane] (Danio rerio)

ras-2 [plasma membrane] (Caenorhabditis elegans)

MRAS [plasma membrane] (Bos taurus)

MRAS [plasma membrane] (Gallus gallus)

MRAS [plasma membrane] (Sus scrofa)

S-GGC MRAS [plasma membrane] (Mus musculus)

S-GGC MRAS [plasma membrane] (Rattus norvegicus)

Modified Residues

Name

S-geranylgeranyl-L-cysteine (geranylgeranyl group) at 205

Coordinate

205

Modification

geranylgeranyl group

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

NP_001078518.1, NP_036351.3, NP_001239019.1, NP_001239021.1, XP_005247285.1, NP_001239022.1, XP_016861376.1, NP_001239020.1

OpenTargets

ENSG00000158186

HPA

ENSG00000158186-MRAS

GeneCards

O14807

Ensembl

ENSP00000419582, ENST00000621127, ENSG00000158186, ENSP00000481637, ENST00000614350, ENSP00000389682, ENST00000464896, ENSP00000484586, ENSP00000418356, ENST00000474559, ENSP00000289104, ENST00000423968, ENST00000289104

PRO

O14807

Pharos - Targets

O14807

PDB

7TXH, 7UPI, 7SD0, 7TVF