24211266 |
An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth
Young, LC,
Ghatrora, R,
Gewinner, C,
Bender, S,
Hartig, N,
Burlingame, AL,
Oses-Prieto, JA,
Henderson, S,
Vijayakumar, V,
Jathoul, AP,
Vietri Rudan, M,
Rodriguez-Viciana, P,
Lythgoe, MF,
Muñoz-Alegre, M,
Durdu, S
|
Mol. Cell |
2013 |
16041367 |
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration
Brinkmann, V,
Hekman, M,
Wunder, C,
Sievers, C,
Rudel, T,
Rajalingam, K,
Churin, Y,
Rapp, UR
|
Nat. Cell Biol. |
2005 |
25907612 |
Regulation of RAF protein kinases in ERK signalling
Lavoie, H,
Therrien, M
|
Nat. Rev. Mol. Cell Biol. |
2015 |
27264673 |
A novel rasopathy caused by recurrent de novo missense mutations in PPP1CB closely resembles Noonan syndrome with loose anagen hair
Aldinger, KA,
Bennett, JT,
Sol-Church, K,
Baker, L,
Timms, AE,
Powell-Hamilton, N,
Dobyns, WB,
Gripp, KW,
Tusi, J,
Stabley, D
|
Am. J. Med. Genet. A |
2016 |
24347342 |
Prohibitins role in cellular survival through Ras-Raf-MEK-ERK pathway
Thomas, K,
Chowdhury, I,
Thompson, WE
|
J. Cell. Physiol. |
2014 |
28289718 |
Elucidation of MRAS-mediated Noonan syndrome with cardiac hypertrophy
Tester, DJ,
Sol-Church, K,
Higgins, EM,
MacRae, CA,
Mason-Suares, H,
Ackerman, JP,
Bos, JM,
Urrutia, R,
Gripp, KW,
Ackerman, MJ
|
JCI Insight |
2017 |
16294014 |
Ras-Raf signaling needs prohibitin
Rudel, T,
Rajalingam, K
|
Cell Cycle |
2005 |
28666118 |
RAS Proteins and Their Regulators in Human Disease
McCormick, F,
Nissley, DV,
Simanshu, DK
|
Cell |
2017 |
19684605 |
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair
Zenker, M,
Martinelli, S,
Di Schiavi, E,
Cordeddu, V,
Ferrero, GB,
Cardinale, A,
Bartholdi, D,
Merlo, D,
Anichini, C,
Iyengar, R,
Tartaglia, M,
Tenconi, R,
Schackwitz, W,
Cecchetti, S,
Digilio, MC,
Gelb, BD,
Zampino, G,
Pennacchio, LA,
Bazzicalupo, P,
Sarkozy, A,
Ma'ayan, A,
Kutsche, K,
Fodale, V,
Lipzen, A,
Dallapiccola, B,
Flex, E,
Lepri, F,
Martin, J,
Selicorni, A,
Rossi, C,
Mazzanti, L
|
Nat. Genet. |
2009 |
12932319 |
Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites
Veenstra, TD,
Ory, S,
Zhou, M,
Morrison, DK,
Conrads, TP
|
Curr Biol |
2003 |
14530258 |
Membrane localization, oligomerization, and phosphorylation are required for optimal raf activation
O'Neil, JJ,
Farrar, MA,
Goetz, CA
|
J. Biol. Chem. |
2003 |
16630891 |
A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity
McCormick, F,
Fried, M,
Burlingame, A,
Oses-Prieto, J,
Rodriguez-Viciana, P
|
Mol. Cell |
2006 |
11756411 |
Dephosphorylation of Ser-259 regulates Raf-1 membrane association
Kubicek, M,
Baccarini, M,
Abraham, D,
Pacher, M,
Eulitz, M,
Podar, K
|
J Biol Chem |
2002 |
21779496 |
Raf family kinases: old dogs have learned new tricks
Romano, D,
Matallanas, D,
Rauch, J,
Zebisch, A,
Birtwistle, M,
Kolch, W,
von Kriegsheim, A
|
Genes Cancer |
2011 |