OGG1beta translocates to mitochondria

Stable Identifier
R-HSA-9656947
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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OGG1beta translocates to mitochondria
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OGG1 splicing isoform beta contains a mitochondrial targeting sequence at the N-terminus and lacks the C-terminal nuclear localization signal. OGG1beta localizes to mitochondria (Nishioka et al. 1999).
Literature References
PubMed ID Title Journal Year
10233168 Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs

Nishioka, K, Fujiwara, T, Oda, H, Sugimachi, K, Ohtsubo, T, Nakabeppu, Y, Kang, D

Mol. Biol. Cell 1999
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Authored
Orlic-Milacic, M  (2019-07-30)
Reviewed
Vlahopoulos, S  (2019-10-02)
Boldogh, I  (2019-10-08)
Created
Orlic-Milacic, M  (2019-08-06)
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