Transcription of DDIT3 (CHOP, GADD153) in response to heme deficiency

Stable Identifier
R-HSA-9655071
Type
Reaction [uncertain]
Species
Homo sapiens
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The DDIT3 gene is transcribed to yield mRNA. Transcription of DDIT3 is activated by ATF4 in response to heme deficiency, which activates ATF4 expression via the integrated stress kinase EIF2AK1 (HRI) (inferred from the mouse, rat, and hamster homologs).

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