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ATF4 and a CEBP protein bind the ATF5 promoter
Stable Identifier
R-HSA-9653742
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Response of EIF2AK1 (HRI) to heme deficiency (Homo sapiens)
ATF4 and a CEBP protein bind the ATF5 promoter (Homo sapiens)
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ATF4 and a member of the CEBP family of transcription factors (CEBPB, CEBPG, or DDIT3, also known as CHOP) bind as a heterodimer to a composite CEBP-ATF element in the promoter of the ATF5 gene (inferred from mouse homologs).
Participants
Input
ATF4 [nucleoplasm]
(Homo sapiens)
ATF5 gene [nucleoplasm]
(Homo sapiens)
CEBPB,CEBPG,DDIT3 [nucleoplasm]
(Homo sapiens)
Output
ATF4:CEBPB,CEBPG,DDIT3:ATF5 gene [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Response of EIF2AK1 (HRI) to heme deficiency (Homo sapiens)
Inferred From
Atf4 and a Cebp protein bind the Atf5 gene (Mus musculus)
Authored
May, B (2019-07-14)
Reviewed
Chen, JJ (2019-10-22)
Created
May, B (2019-07-15)
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