Transcription of ATF5

Stable Identifier
R-HSA-9653724
Type
Reaction [omitted]
Species
Homo sapiens
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The ATF5 gene is transcribed to yield mRNA (Watatani et al. 2007, Wei et al. 2010, and inferred from the mouse homolog). Transcription of ATF5 is activated by a heterodimer of ATF4 and a CEBP factor in response to proteasome inhibition, heme deficiency, endoplasmic reticulum stress, and amino acid deficiency (inferred from mouse homologs).

Literature References
PubMed ID Title Journal Year
17140605 Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level

Watatani, Y, Kimura, N, Shimizu, YI, Akiyama, I, Tonaki, D, Hirose, H, Takahashi, S, Takahashi, Y

Life Sci. 2007
20423929 Identification and characterization of the promoter of human ATF5 gene

Wei, Y, Ge, Y, Zhou, F, Chen, H, Cui, C, Liu, D, Yang, Z, Wu, G, Gu, J, Jiang, J

J. Biochem. 2010
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