2xPNPO:2xFMN oxidizes PDXP to PXLP

Stable Identifier
R-HSA-965019
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
PLP from oxidation of pyridoxine phosphate
ReviewStatus
5/5
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2xPNPO:2xFMN oxidizes PDXP to PXLP
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Pyridoxine-5'-phosphate oxidase (PNPO) is able to oxidize pyridoxine phosphate (PDXP) to pyridoxal 5'-phosphate (PXLP) (Kang et al. 2004).

Literature References
PubMed ID Title Journal Year
15182361 Genomic organization, tissue distribution and deletion mutation of human pyridoxine 5'-phosphate oxidase

Won, MH, Hong, ML, Kang, TC, Moon, BJ, Kim, DW, Kang, JH, Kwon, OS, Choi, SY, Park, J, Baek, NI

Eur J Biochem 2004
Participants
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Output
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as an event of
Catalyst Activity

pyridoxamine-phosphate oxidase activity of 2xPNPO:2xFMN [cytosol]

Physical Entity
2xPNPO:2xFMN [cytosol] (Homo sapiens)
Activity
pyridoxamine-phosphate oxidase activity (GO:0004733)
Orthologous Events
2xPNPO:2xFMN oxidizes PDXP to PXLP (Bos taurus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Caenorhabditis elegans)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Canis familiaris)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Danio rerio)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Dictyostelium discoideum)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Drosophila melanogaster)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Gallus gallus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Mus musculus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Rattus norvegicus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Saccharomyces cerevisiae)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Schizosaccharomyces pombe)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Sus scrofa)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Xenopus tropicalis)
Cross References
Rhea
Authored
Stephan, R  (2010-09-18)
Reviewed
D'Eustachio, P  (2010-11-08)
Created
Jassal, B  (2010-09-20)
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