Reactome | 2xPDXK:2xZn2+ phosphorylates PXL

2xPDXK:2xZn2+ phosphorylates PXL

Stable Identifier

R-HSA-964970

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PLP results from phosphorylation of pyridoxal

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Pyridoxal kinase (PDXK) catalyzes the ATP-dependent phosphorylation of pyridoxal (PXL) to form pyridoxal 5'-phosphate (PXLP) (Lee et al. 2000, di Salvo et al. 2004).

Literature References

PubMed ID	Title	Journal	Year
10987144	Human pyridoxal kinase: overexpression and properties of the recombinant enzyme Moon, BJ, Kwon, OS, Lee, HS, Choi, SY	Mol Cells	2000
15249053	Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases di Salvo, ML, Schirch, V, Hunt, S	Protein Expr Purif	2004