NRAS G12A [plasma membrane]

Stable Identifier
R-HSA-9649657
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
NRAS G12A [plasma membrane] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
NRAS, HRAS1
Chain
chain:1-186, propeptide:187-189
Reference Transcript
Other Identifiers
11719188_at
11719189_at
1539_at
16691262
202647_PM_s_at
202647_s_at
224985_PM_at
224985_at
2429260
2429262
2429263
2429264
2429265
2429266
2429267
2429268
2429270
2429271
2429273
2429274
4893
7918813
A_23_P63190
A_33_P3317825
GE79523
GO:0000139
GO:0000165
GO:0000166
GO:0001938
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0007165
GO:0007265
GO:0016020
GO:0016787
GO:0019003
GO:0023052
GO:0030154
GO:0031410
GO:0043226
GO:0044877
GO:0045445
GO:0048856
GO:0070062
GO:0070821
GO:0098772
HMNXSV003016401
Hs.260523.1.A1_3p_at
ILMN_1775759
PH_hs_0013620
TC01003014.hg
X02751_at
g6006027_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
glycine 12 replaced with L-alanine
Coordinate
12
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-alanine.
A protein modification that effectively removes or replaces an glycine.
Disease
Name Identifier Synonyms
lung cancer DOID:1324
colorectal cancer DOID:9256
melanoma DOID:1909 Naevocarcinoma, melanoma, melanoma, malignant melanoma, morphology (morphologic abnormality), malignant melanoma NOS (morphologic abnormality), malignant melanoma (disorder), malignant melanoma, malignant melanoma, malignant melanoma, malignant melanoma
hematologic cancer DOID:2531 hematopoietic cancer, hematopoietic tumors, Hematologic neoplasm (disorder), Hematologic malignancy, hematopoietic neoplasm (morphologic abnormality), Hematologic malignancy (disorder), Hematological tumors, blood cancer, hematopoietic and lymphoid system tumor, malignant hematopoietic neoplasm (morphologic abnormality)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
COSMIC
IntEnz
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (7)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  20 0.925 12
 UniProt:P15056 BRAF  20 0.806 6
 UniProt:Q8WTS1 ABHD5  2 0.527 2
 UniProt:Q99N57  11 0.499 2
 UniProt:P28028  6 0.499 2
 UniProt:Q658P3 STEAP3  2 0.483 2
 UniProt:P01116 KRAS  20 0.483 2
Cite Us!