Reactome | DEPDC5 [lysosomal membrane]

DEPDC5 [lysosomal membrane]

Stable Identifier

R-HSA-9638222

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

fullName evidence="20"GATOR complex protein DEPDC5, DEPD5_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75140 DEPDC5

Gene Names

DEPDC5, KIAA0645

Chain

chain:1-1603

Reference Genes

BioGPS Gene:9681 DEPDC5

COSMIC (genes):DEPDC5 DEPDC5

CTD Gene:9681 DEPDC5

dbSNP Gene:9681 DEPDC5

ENSEMBL:ENSG00000100150 DEPDC5

HGNC:18423 DEPDC5

KEGG:hsa:9681 DEPDC5

Monarch:9681 DEPDC5

NCBI Gene:9681 DEPDC5

OMIM:614191 DEPDC5

UCSC:O75140 DEPDC5

Reference Transcript

Participates

as a component of

GATOR1 [lysosomal membrane] (Homo sapiens)

Inferred To

depdc5 [lysosomal membrane] (Xenopus tropicalis)

Depdc5 [lysosomal membrane] (Mus musculus)

Depdc5 [lysosomal membrane] (Rattus norvegicus)

DEPDC5 [lysosomal membrane] (Bos taurus)

DEPDC5 [lysosomal membrane] (Canis familiaris)

DEPDC5 [lysosomal membrane] (Dictyostelium discoideum)

DEPDC5 [lysosomal membrane] (Gallus gallus)

DEPDC5 [lysosomal membrane] (Sus scrofa)

Cross References

OpenTargets

ENSG00000100150

ENSEMBL

ENSP00000440210, ENSP00000383108, ENST00000382112, ENST00000382111, ENST00000645711, ENST00000400242, ENSP00000493489, ENSP00000494406, ENST00000642696, ENSP00000383107, ENSP00000495917, ENST00000651528, ENST00000535622, ENSP00000496532, ENSP00000371545, ENST00000644331, ENST00000646755, ENST00000400248, ENSG00000100150, ENSP00000383101, ENST00000400249, ENSP00000371546, ENSP00000498382

HPA

ENSG00000100150-DEPDC5

GeneCards

DEPDC5

PRO

O75140

Pharos - Targets

O75140

GlyGen

O75140

PDB

7T3A, 6CES, 7T3C, 8FW5, 7T3B, 6CET