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SEH1L [lysosomal membrane]
Stable Identifier
R-HSA-9638217
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
fullName evidence="17"Nucleoporin SEH1, SEH1_HUMAN
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
RRAGA,B hydrolyzes GTP (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR1 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2:CASTOR1:CASTOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
SESN1,2 binds L-leucine and dissociates from GATOR2 (Homo sapiens)
KICSTOR:GATOR1:GATOR2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
KICSTOR:GATOR1:GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2:SESN1,2 [lysosomal membrane] (Homo sapiens)
GATOR2 [lysosomal membrane] (Homo sapiens)
SEH1L [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96EE3 SEH1L
Gene Names
SEH1L, SEC13L, SEH1
Chain
chain:1-360
Reference Genes
BioGPS Gene:81929 SEH1L
COSMIC (genes):SEH1L SEH1L
CTD Gene:81929 SEH1L
dbSNP Gene:81929 SEH1L
ENSEMBL:ENSG00000085415 SEH1L
HGNC:30379 SEH1L
KEGG:hsa:81929 SEH1L
Monarch:81929 SEH1L
NCBI Gene:81929 SEH1L
OMIM:609263 SEH1L
UCSC:Q96EE3 SEH1L
Reference Transcript
RefSeq:NM_031216.3 SEH1L
RefSeq:NM_001013437.1 SEH1L
Participates
as a component of
GATOR2 [lysosomal membrane] (Homo sapiens)
Inferred To
seh1l [lysosomal membrane]
(Xenopus tropicalis)
SEH1L [lysosomal membrane]
(Bos taurus)
SEH1L [lysosomal membrane]
(Dictyostelium discoideum)
SEH1L [lysosomal membrane]
(Gallus gallus)
CEP192 [lysosomal membrane]
(Sus scrofa)
Seh1l [lysosomal membrane]
(Mus musculus)
Ghost homologue of SEH1L [lysosomal membrane]
(Canis familiaris)
Ghost homologue of SEH1L [lysosomal membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001013455.1
,
NP_112493.2
ENSEMBL
ENSP00000262124
,
ENST00000399892
,
ENSG00000085415
,
ENST00000262124
,
ENSP00000382779
OpenTargets
ENSG00000085415
GeneCards
SEH1L
HPA
ENSG00000085415-SEH1L
PRO
Q96EE3
Pharos - Targets
Q96EE3
GlyGen
Q96EE3
PDB
7UHY
,
7R5K
,
5A9Q
,
7PEQ
,
7R5J
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P55735 SEC13
4
SEC13 [cytosol]
(R-HSA-203981)
SEC13 [endoplasmic reticulum membrane]
(R-HSA-203994)
SEC13 [ER to Golgi transport vesicle membrane]
(R-HSA-204012)
SEC13 [lysosomal membrane]
(R-HSA-9638246)
0.775
8
UniProt:Q8WYP5 AHCTF1
1
AHCTF1 [cytosol]
(R-HSA-376244)
0.488
3
UniProt:P04578 env
7
ENV [viral envelope]
(R-HIV-173439)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
0.462
2
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