Reactome | SEH1L [lysosomal membrane]

SEH1L [lysosomal membrane]

Stable Identifier

R-HSA-9638217

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

fullName evidence="17"Nucleoporin SEH1, SEH1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96EE3 SEH1L

Gene Names

SEH1L, SEC13L, SEH1

Chain

chain:1-360

Reference Genes

BioGPS Gene:81929 SEH1L

COSMIC (genes):SEH1L SEH1L

CTD Gene:81929 SEH1L

dbSNP Gene:81929 SEH1L

ENSEMBL:ENSG00000085415 SEH1L

HGNC:30379 SEH1L

KEGG Gene (Homo sapiens):81929 SEH1L

Monarch:81929 SEH1L

NCBI Gene:81929 SEH1L

OMIM:609263 SEH1L

UCSC:Q96EE3 SEH1L

Reference Transcript

Other Identifiers

0000670064

11734049_a_at

11756649_a_at

16851121

221931_s_at

223225_s_at

3779775

3779776

3779777

3779779

3779780

3779782

3779783

3779785

3779788

3779789

3779791

3779793

3779794

3779795

3779796

3779797

3779798

3779799

62547_at

63808_at

8020254

81929

A_23_P78311

A_24_P407930

A_33_P3409934

GE79661

GO:0000278

GO:0000775

GO:0000776

GO:0000777

GO:0003674

GO:0005198

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005643

GO:0005694

GO:0005737

GO:0005764

GO:0005765

GO:0005773

GO:0005829

GO:0005975

GO:0006091

GO:0006110

GO:0006406

GO:0006409

GO:0006464

GO:0006810

GO:0006913

GO:0006950

GO:0006999

GO:0007010

GO:0007049

GO:0007052

GO:0007059

GO:0007080

GO:0007084

GO:0007165

GO:0008150

GO:0009056

GO:0015031

GO:0016020

GO:0016032

GO:0016925

GO:0019058

GO:0019083

GO:0031080

GO:0032008

GO:0032991

GO:0034198

GO:0034629

GO:0034641

GO:0035859

GO:0043226

GO:0043657

GO:0044281

GO:0044403

GO:0050830

GO:0051028

GO:0051276

GO:0051301

GO:0051315

GO:0060964

GO:0061024

GO:0061700

GO:0075733

GO:0140014

GO:1900034

GO:1904263

HMNXSV003018203

HMNXSV003035121

HMNXSV003043703

Hs.301048.0.S1_3p_s_at

Hs.301048.1.A1_3p_s_at

ILMN_1705032

ILMN_1708619

ILMN_2381138

PH_hs_0015504

TC18000069.hg

Participates

as a component of

GATOR2 [lysosomal membrane] (Homo sapiens)

Inferred To

seh1l [lysosomal membrane] (Danio rerio)

SEH1L [lysosomal membrane] (Dictyostelium discoideum)

SEH1L [lysosomal membrane] (Gallus gallus)

SEH1L [lysosomal membrane] (Xenopus tropicalis)

Seh1l [lysosomal membrane] (Mus musculus)

Ghost homologue of SEH1L [lysosomal membrane] (Canis familiaris)

Ghost homologue of SEH1L [lysosomal membrane] (Rattus norvegicus)

Ghost homologue of SEH1L [lysosomal membrane] (Sus scrofa)

Cross References

RefSeq

NP_001013455.1, NP_112493.2

OpenTargets

ENSG00000085415

GeneCards

Q96EE3

HPA

ENSG00000085415-SEH1L

Ensembl

ENSP00000262124, ENSP00000382779, ENSG00000085415, ENST00000262124, ENST00000399892

PRO

Q96EE3

Pharos - Targets

Q96EE3

GlyGen

Q96EE3

PDB

5A9Q

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55735 SEC13	4	SEC13 [ER to Golgi transport vesicle membrane] (R-HSA-204012) SEC13 [cytosol] (R-HSA-203981) SEC13 [endoplasmic reticulum membrane] (R-HSA-203994) SEC13 [lysosomal membrane] (R-HSA-9638246)	0.621	3
UniProt:Q8WYP5 AHCTF1	1	AHCTF1 [cytosol] (R-HSA-376244)	0.488	3
UniProt:P04578 env	7	Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Surface protein gp120 [viral envelope] (R-HIV-171211) ENV [viral envelope] (R-HIV-173439)	0.462	2