Reactome | SEH1L [lysosomal membrane]

SEH1L [lysosomal membrane]

Stable Identifier

R-HSA-9638217

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

fullName evidence="17"Nucleoporin SEH1, SEH1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96EE3 SEH1L

Gene Names

SEH1L, SEC13L, SEH1

Chain

chain:1-360

Reference Genes

BioGPS Gene:81929 SEH1L

COSMIC (genes):SEH1L SEH1L

CTD Gene:81929 SEH1L

dbSNP Gene:81929 SEH1L

ENSEMBL:ENSG00000085415 SEH1L

HGNC:30379 SEH1L

KEGG:hsa:81929 SEH1L

Monarch:81929 SEH1L

NCBI Gene:81929 SEH1L

OMIM:609263 SEH1L

UCSC:Q96EE3 SEH1L

Reference Transcript

Participates

as a component of

GATOR2 [lysosomal membrane] (Homo sapiens)

Inferred To

seh1l [lysosomal membrane] (Xenopus tropicalis)

SEH1L [lysosomal membrane] (Bos taurus)

SEH1L [lysosomal membrane] (Dictyostelium discoideum)

SEH1L [lysosomal membrane] (Gallus gallus)

CEP192 [lysosomal membrane] (Sus scrofa)

Seh1l [lysosomal membrane] (Mus musculus)

Ghost homologue of SEH1L [lysosomal membrane] (Canis familiaris)

Ghost homologue of SEH1L [lysosomal membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001013455.1, NP_112493.2

ENSEMBL

ENSP00000262124, ENST00000399892, ENSG00000085415, ENST00000262124, ENSP00000382779

OpenTargets

ENSG00000085415

GeneCards

SEH1L

HPA

ENSG00000085415-SEH1L

PRO

Q96EE3

Pharos - Targets

Q96EE3

GlyGen

Q96EE3

PDB

7UHY, 7R5K, 5A9Q, 7PEQ, 7R5J

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55735 SEC13	4	SEC13 [cytosol] (R-HSA-203981) SEC13 [endoplasmic reticulum membrane] (R-HSA-203994) SEC13 [ER to Golgi transport vesicle membrane] (R-HSA-204012) SEC13 [lysosomal membrane] (R-HSA-9638246)	0.775	8
UniProt:Q8WYP5 AHCTF1	1	AHCTF1 [cytosol] (R-HSA-376244)	0.488	3
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	2