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Phagocyte cell death caused by cytosolic Mtb
Stable Identifier
R-HSA-9637698
Type
Pathway
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
ReviewStatus
5/5
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Escape of Mtb from the phagocyte (Homo sapiens)
Phagocyte cell death caused by cytosolic Mtb (Homo sapiens)
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Mycobacterium tuberculosis (Mtb), when located in the cytosol of phagocytes, induce cell death similar to necrosis as a means to exit the host cell, ultimately spreading the infection (Moraco & Kornfeld 2014).
Literature References
PubMed ID
Title
Journal
Year
25453227
Cell death and autophagy in tuberculosis
Kornfeld, H
,
Moraco, AH
Semin. Immunol.
2014
Participants
Events
CpnT hydrolyses NAD+
(Homo sapiens)
Participates
as an event of
Escape of Mtb from the phagocyte (Homo sapiens)
Event Information
Go Biological Process
symbiont-mediated killing of host cell (0001907)
Disease
Name
Identifier
Synonyms
tuberculosis
DOID:399
tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R (2019-02-06)
Reviewed
Wilkinson, RJ (2019-10-23)
Deffur, A (2019-10-23)
Created
Jassal, B (2019-02-19)
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