Modulation by Mtb of host immune system

Stable Identifier
R-HSA-9637628
Type
Pathway
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Modulation by Mtb of host immune system
Click the image above or here to open this pathway in the Pathway Browser

Mtb enhances its chances for being taken up by a phagocyte by blocking adaptive immune responses, as well as other innate immune system responses. Components of the bacterial cell wall also specifically promote phagocytosis via both the opsonic pathway and the presentation of adhesins (Esparza et al. 2015).

Literature References
PubMed ID Title Journal Year
25359607 PstS-1, the 38-kDa Mycobacterium tuberculosis glycoprotein, is an adhesin, which binds the macrophage mannose receptor and promotes phagocytosis

Esparza, M, Palomares, B, García, T, Espinosa, P, Zenteno, E, Mancilla, R

Scand. J. Immunol. 2015
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
modulation by symbiont of host defense response (0052031)
Disease
Name Identifier Synonyms
tuberculosis 399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-19)
Reviewed
Deffur, A  (2019-10-23)
Wilkinson, RJ  (2019-10-23)
Created
Pardo, AM  (2019-02-19)
Cite Us!