Modulation by Mtb of host immune system

Stable Identifier
R-HSA-9637628
Type
Pathway
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
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Mtb enhances its chances for being taken up by a phagocyte by blocking adaptive immune responses, as well as other innate immune system responses. Components of the bacterial cell wall also specifically promote phagocytosis via both the opsonic pathway and the presentation of adhesins (Esparza et al. 2015).

Literature References
PubMed ID Title Journal Year
25359607 PstS-1, the 38-kDa Mycobacterium tuberculosis glycoprotein, is an adhesin, which binds the macrophage mannose receptor and promotes phagocytosis

Esparza, M, Palomares, B, GarcĂ­a, T, Espinosa, P, Zenteno, E, Mancilla, R

Scand. J. Immunol. 2015
Participants
Participant Of
Event Information
Disease
Name Identifier Synonyms
tuberculosis 399 tuberculous abscess, Tuberculoma (finding), tuberculoma
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