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RAB7A [phagocytic vesicle membrane]
Stable Identifier
R-HSA-9636586
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
phagocytic vesicle membrane
Synonyms
Ras-related protein Rab-7a, RAB7A_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q02535 ID3
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Response of Mtb to phagocytosis (Homo sapiens)
Suppression of autophagy (Homo sapiens)
SapM binds RAB7A (Homo sapiens)
RAB7A [phagocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51149 RAB7A
Gene Names
RAB7A, RAB7
Chain
initiator methionine:, chain:2-207
Reference Genes
BioGPS Gene:7879 RAB7A
COSMIC (genes):RAB7A RAB7A
CTD Gene:7879 RAB7A
dbSNP Gene:7879 RAB7A
ENSEMBL:ENSG00000075785 RAB7A
HGNC:9788 RAB7A
KEGG:hsa:7879 RAB7A
Monarch:7879 RAB7A
NCBI Gene:7879 RAB7A
OMIM:602298 RAB7A
UCSC:P51149 RAB7A
Reference Transcript
RefSeq:NM_004637.5 RAB7A
Other Identifiers
11722811_s_at
11722812_s_at
11753390_x_at
1570061_PM_at
1570061_at
16945241
211960_PM_s_at
211960_s_at
211961_PM_s_at
211961_s_at
2641264
2641283
2641284
2641285
2641286
2641287
2641288
2641289
2641293
2641294
2641295
2641296
2641297
2641298
2641300
2641301
2641302
2641303
2641304
2641305
2641309
2641310
2641311
2641312
2641313
2641314
45003_r_at
7879
8082431
A_14_P133140
A_24_P234572
A_33_P3361851
GE62295
GE905794
GO:0000045
GO:0000166
GO:0000421
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005737
GO:0005739
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005773
GO:0005794
GO:0005811
GO:0005829
GO:0005886
GO:0006622
GO:0006629
GO:0006886
GO:0006897
GO:0006914
GO:0007174
GO:0008333
GO:0009617
GO:0010008
GO:0015031
GO:0016020
GO:0016042
GO:0016192
GO:0016787
GO:0019003
GO:0019076
GO:0022615
GO:0030163
GO:0030667
GO:0030670
GO:0030672
GO:0030904
GO:0031267
GO:0031410
GO:0031902
GO:0031966
GO:0033162
GO:0034045
GO:0036466
GO:0042147
GO:0043226
GO:0043231
GO:0045022
GO:0045335
GO:0045453
GO:0045732
GO:0046907
GO:0048524
GO:0051650
GO:0061024
GO:0061724
GO:0070062
GO:0072659
GO:0090382
GO:0090383
GO:0090385
GO:0097208
GO:0098772
GO:0098830
GO:0098943
GO:0098978
GO:0099003
GO:0099638
GO:1903542
GO:1903543
GO:1905366
GO:1905394
HMNXSV003026071
Hs.237955.3.S1_3p_a_at
Hs.237955.3.S2_3p_at
Hs2.372904.1.S1_3p_at
ILMN_1716524
PH_hs_0017281
TC03000677.hg
X93499_at
Participates
as a component of
SapM:RAB7 [phagocytic vesicle membrane] (Homo sapiens)
as an input of
SapM binds RAB7A (Homo sapiens)
Other forms of this molecule
RAB7A [secretory granule membrane]
RAB7A [plasma membrane]
RAB7A [cytosol]
RAB7A [lysosomal membrane]
GGC-RAB7A [cytosol]
GGC-RAB7A [lysosomal membrane]
Cross References
OpenTargets
ENSG00000075785
ENSEMBL
ENST00000676214
,
ENST00000265062
,
ENSP00000501618
,
ENSP00000265062
,
ENST00000674589
,
ENSP00000502000
,
ENSP00000502088
,
ENSP00000502486
,
ENST00000675342
,
ENST00000675497
HPA
ENSG00000075785-RAB7A
PRO
P51149
Pharos - Targets
P51149
GlyGen
P51149
Orphanet
RAB7A
PDB
1YHN
,
3LAW
,
1T91
,
6IYB
,
6WCW
,
7F6J
Interactors (25)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96NA2 RILP
1
RILP [lysosomal membrane]
(R-HSA-2213229)
0.926
11
UniProt:Q9Y4G2 PKHM1
0.803
11
UniProt:P31150 GDI1
1
GDI1 [cytosol]
(R-HSA-195106)
0.725
6
UniProt:Q9BXW6 OSBPL1A
1
OSBPL1A [cytosol]
(R-HSA-2213214)
0.672
5
UniProt:Q9NVJ2 ARL8B
0.597
7
UniProt:P86791 CCZ1
1
CCZ1 [cytosol]
(R-HSA-8877441)
0.59
2
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
11
UniProt:Q9UNE7 STUB1
1
STUB1 [cytosol]
(R-HSA-975970)
0.556
3
UniProt:Q9UNS2 COPS3
2
COPS3 [nucleoplasm]
(R-HSA-5697017)
COPS3 [cytosol]
(R-HSA-416973)
0.556
3
UniProt:Q9GZS3 SKIC8
2
WDR61 [cytosol]
(R-HSA-8931534)
WDR61 [nucleoplasm]
(R-HSA-8866696)
0.556
3
UniProt:Q02535 ID3
1
ID3 [nucleoplasm]
(R-HSA-9613379)
0.556
3
UniProt:Q6ZR37 PKHG7
0.556
3
UniProt:Q8WXF7 ATLA1
0.556
3
UniProt:O75348 ATP6V1G1
1
ATP6V1G1 [cytosol]
(R-HSA-912578)
0.527
2
UniProt:P61421 ATPV0D1
3
ATP6V0D1 [endosome membrane]
(R-HSA-912592)
ATP6V0D1 [phagocytic vesicle membrane]
(R-HSA-1222571)
ATP6V0D1 [lysosomal membrane]
(R-HSA-9640177)
0.527
2
UniProt:P0DTD1-PRO_0000449625 REP
0.527
2
UniProt:P61019 RAB2A
3
GGC-RAB2A [cytosol]
(R-HSA-8873963)
RAB2A [cytosol]
(R-HSA-8873716)
RAB2A [Golgi membrane]
(R-HSA-2422386)
0.527
2
UniProt:P21796 VDAC1
7
p-S65-Ub:VDAC1 [mitochondrial outer membrane]
(R-HSA-9834991)
K63polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834037)
K48polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-5205624)
Ub-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834989)
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
VDAC1 [mitochondrial intermembrane space]
(R-HSA-1267960)
PolyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-6783079)
0.527
2
UniProt:P21281 ATP6V1B2
1
ATP6V1B2 [cytosol]
(R-HSA-912598)
0.527
2
UniProt:Q5ZU30 SETA
0.525
2
UniProt:Q96JC1 VPS39
1
VPS39 [endosome membrane]
(R-HSA-2197806)
0.499
2
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
6
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE
0.462
2
UniProt:A0A0F6B1Q8 A0A0F6B1Q8
0.462
2
ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE
0.462
2
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