SapM dephosphorylates PI3P

Stable Identifier
R-HSA-9636457
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SapM dephosphorylates PI3P
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Phosphatidylinositol-3-phosphatase (SapM) catalyzes the dephoshorylation of phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol (PI) (Vergne et al. 2005).
Literature References
PubMed ID Title Journal Year
15753315 Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

Deretic, V, Belisle, J, Lucas, M, Vergne, I, Lee, HH, Chua, J

Proc. Natl. Acad. Sci. U.S.A. 2005
Participants
Input
Output
Participates
as an event of
Catalyst Activity

phosphatase activity of sapM [cytosol]

Physical Entity
sapM [cytosol] (Mycobacterium tuberculosis)
Activity
phosphatase activity (GO:0016791)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-13)
Cite Us!