SapM dephosphorylates PI3P

Stable Identifier
R-HSA-9636457
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
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Phosphatidylinositol-3-phosphatase (SapM) catalyzes the dephoshorylation of phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol (PI) (Vergne et al. 2005).

Literature References
PubMed ID Title Journal Year
15753315 Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

Vergne, I, Chua, J, Lee, HH, Lucas, M, Belisle, J, Deretic, V

Proc. Natl. Acad. Sci. U.S.A. 2005
Participants
Participates
Catalyst Activity

phosphatase activity of sapM [cytosol]

Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Reviewed
Created
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