SapM dephosphorylates PI3P

Stable Identifier
R-HSA-9636457
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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SapM dephosphorylates PI3P
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Phosphatidylinositol-3-phosphatase (SapM) catalyzes the dephoshorylation of phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol (PI) (Vergne et al. 2005).
Literature References
PubMed ID Title Journal Year
15753315 Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

Vergne, I, Chua, J, Lee, HH, Lucas, M, Belisle, J, Deretic, V

Proc. Natl. Acad. Sci. U.S.A. 2005
Participants
Input
Output
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as an event of
Catalyst Activity

phosphatase activity of SapM [cytosol]

Physical Entity
SapM [cytosol] (Mycobacterium tuberculosis)
Activity
phosphatase activity (GO:0016791)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Cross References
Mondo
Authored
Stephan, R  (2019-02-06)
Reviewed
Deffur, A  (2019-10-23)
Wilkinson, RJ  (2019-10-23)
Created
Koile, I  (2019-02-13)
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