Mce3E binds MAPK3

Stable Identifier
R-HSA-9636304
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
endoplasmic reticulum lumen
ReviewStatus
5/5
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Mce3E binds MAPK3
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Mtb Mce-family lipoprotein Mce3E (Mce3E) translocates to the phagocyte's endoplasmic reticulum (ER) and binds to newly produced human mitogen activated protein kinase 3 (MAPK3), inhibiting its transport out of the ER (Li et al. 2015).

Literature References
PubMed ID Title Journal Year
25780035 Mycobacterium tuberculosis Mce3E suppresses host innate immune responses by targeting ERK1/2 signaling

Wang, J, Qiu, XB, Chai, QY, Zhang, Y, Li, BX, Li, J, Liu, CH

J. Immunol. 2015
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-12)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Pardo, AM  (2019-02-12)
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