PPE2 binds KPNA1:KPNB1

Stable Identifier
R-HSA-9636251
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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PPE2 binds KPNA1:KPNB1
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PPE family protein PPE2 is transported via the importin-α/β (KPNA1:KPNB1) pathway, from the cytosol to the nucleoplasm. The first step is the binding of PPE2 to KPNA1:KPNB1 (Bhat et al. 2017).
Literature References
PubMed ID Title Journal Year
28071726 The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production

Ghosh, S, Mukhopadhyay, S, Kotturu, SK, Bhat, KH, Srivastava, S

Sci Rep 2017
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-06)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Koile, I  (2019-02-12)
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