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ATF4 binds the CEBPB gene
Stable Identifier
R-HSA-9635936
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Cellular response to starvation (Homo sapiens)
Response of EIF2AK4 (GCN2) to amino acid deficiency (Homo sapiens)
ATF4 binds the CEBPB gene (Homo sapiens)
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ATF4 binds an enhancer downstream of the protein coding region of the CEBPB gene (Chen et al. 2005). The binding site resembles a composite CEBP-ATF element. Therefore ATF4 may form a heterodimer with a CEBP protein at the element (Chen et al. 2005).
Literature References
PubMed ID
Title
Journal
Year
16026328
Amino-acid limitation induces transcription from the human C/EBPbeta gene via an enhancer activity located downstream of the protein coding sequence
Kilberg, MS
,
Gjymishka, A
,
Pan, YX
,
Dudenhausen, E
,
Chen, C
,
Chen, H
Biochem. J.
2005
Participants
Input
ATF4 [nucleoplasm]
(Homo sapiens)
CEBPB gene [nucleoplasm]
(Homo sapiens)
Output
ATF4:CEBPB gene [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Response of EIF2AK4 (GCN2) to amino acid deficiency (Homo sapiens)
Authored
May, B (2019-02-09)
Reviewed
Staschke, KA (2019-11-20)
Bruhat, A (2019-09-15)
Created
May, B (2019-02-10)
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