The CEBPB gene is transcribed to yield mRNA and the mRNA is translated to yield protein (Chen et al. 2005, Lee et al. 2008, Sikalidis et al. 2011). Transcription of CEBPB is activated in response to amino acid deficiency (Chen et al. 2005, Lee et al. 2008, Sikalidis et al. 2011). ATF4 bound to an enhancer downstream of the CEBPB coding region (Chen et al. 2005) increases transcription of CEBPB approximately 4-fold (Chen et al. 2005, Lee et al. 2008, Sikalidis et al. 2011).
Dominy, JE, Sikalidis, AK, Lee, JI, Stipanuk, MH, Hirschberger, LL, Wang, W
Kilberg, MS, Gjymishka, A, Pan, YX, Dudenhausen, E, Chen, C, Chen, H
Sikalidis, AK, Lee, JI, Stipanuk, MH
© 2023 Reactome
