Rv3655c binds RNF213

Stable Identifier
R-HSA-9635609
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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Rv3655c binds RNF213
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Apoptosis inhibitor Rv3655c (Rv3655c) protein is secreted by Mtb and binds to human E3 ubiquitin-protein ligase RNF213 (RNF213) which inhibits the cleavage of caspase-8 (Danelishvili et al. 2010).

Literature References
PubMed ID Title Journal Year
20454556 Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis

Danelishvili, L, Selker, J, Bermudez, LE, Yamazaki, Y

PLoS ONE 2010
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-12)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Pardo, AM  (2019-02-06)
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