Rv3654c binds SFPQ

Stable Identifier
R-HSA-9635446
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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Rv3654c binds SFPQ
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Apoptosis inhibitor Rv3654c (Rv3654c) protein is secreted from Mtb and binds to human polypyrimidine tract binding protein-associated splicing factor (SFPQ), which inhibits the cleavage of caspase-8 (Danelishvili et al. 2010).
Literature References
PubMed ID Title Journal Year
20454556 Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis

Danelishvili, L, Selker, J, Bermudez, LE, Yamazaki, Y

PLoS ONE 2010
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2019-02-12)
Reviewed
Wilkinson, RJ  (2019-10-23)
Deffur, A  (2019-10-23)
Created
Pardo, AM  (2019-02-05)
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