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ARNTL [nucleoplasm]
Stable Identifier
R-HSA-9634872
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Aryl hydrocarbon receptor nuclear translocator-like protein 1, BMAL1, Brain and muscle ARNT-like 1, BHLHE5, MOP3, PASD3
Icon
Locations in the PathwayBrowser for interactor UniProt:Q9Y463 DYR1B
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by NPAS4 (Homo sapiens)
NPAS4 regulates expression of target genes (Homo sapiens)
NPAS4 binds ARNTL (BMAL1) (Homo sapiens)
ARNTL [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00327 ARNTL
Gene Names
ARNTL, BHLHE5, BMAL1, MOP3, PASD3
Chain
chain:1-626
Reference Genes
BioGPS Gene:406 ARNTL
COSMIC (genes):ARNTL ARNTL
CTD Gene:406 ARNTL
dbSNP Gene:406 ARNTL
ENSEMBL:ENSG00000133794 ARNTL
ENSEMBL_homo_sapiens_GENE:ENSG00000133794.20 ARNTL
HGNC:701 ARNTL
KEGG Gene (Homo sapiens):406 ARNTL
Monarch:406 ARNTL
NCBI Gene:406 ARNTL
OMIM:602550 ARNTL
UCSC:O00327 ARNTL
Reference Transcript
RefSeq:NM_001297724.1 ARNTL
RefSeq:XM_017017747.1 ARNTL
RefSeq:NM_001030272.2 ARNTL
RefSeq:XM_017017743.1 ARNTL
RefSeq:NM_001297719.1 ARNTL
RefSeq:XM_011520112.2 ARNTL
RefSeq:XM_017017748.1 ARNTL
RefSeq:NM_001030273.2 ARNTL
RefSeq:XM_017017746.1 ARNTL
RefSeq:NM_001297722.1 ARNTL
RefSeq:XM_011520113.1 ARNTL
RefSeq:XM_017017742.1 ARNTL
RefSeq:NM_001178.5 ARNTL
Other Identifiers
11741091_a_at
11753127_a_at
11755151_a_at
16722217
209824_PM_s_at
209824_s_at
210971_PM_s_at
210971_s_at
3321157
3321158
3321159
3321160
3321173
3321174
3321187
3321193
3321194
3321195
3321197
3321198
3321200
3321201
3321202
3321205
3321206
3321207
3321209
3321210
3321211
3321212
3321213
3321214
3321215
3321216
3321218
3321220
3321225
3321229
3321230
3321231
3321232
3321233
3321234
36896_s_at
406
7938563
AB000816_s_at
A_14_P138600
A_23_P162037
GE54388
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0007283
GO:0007623
GO:0016605
GO:0017162
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0032007
GO:0032922
GO:0033391
GO:0034751
GO:0036211
GO:0042634
GO:0042753
GO:0043161
GO:0043226
GO:0043231
GO:0043565
GO:0045599
GO:0045892
GO:0045893
GO:0045944
GO:0046983
GO:0048511
GO:0048856
GO:0050767
GO:0050796
GO:0051726
GO:0051775
GO:0051879
GO:0070888
GO:0090263
GO:0090403
GO:0120163
GO:0140110
GO:0140297
GO:1901985
GO:1990513
GO:1990837
GO:2000074
GO:2000323
GO:2000772
GO:2001016
HMNXSV003020927
ILMN_1731476
ILMN_2405305
PH_hs_0022167
TC11000206.hg
U60415_at
g2094734_3p_a_at
g2094740_3p_a_at
Participates
as an input of
NPAS4 binds ARNTL (BMAL1) (Homo sapiens)
as a component of
NPAS4:ARNTL [nucleoplasm] (Homo sapiens)
Other forms of this molecule
ARNTL [cytosol]
p-S-ARNTL [nucleoplasm]
Inferred To
cyc [nucleoplasm]
(Drosophila melanogaster)
Bmal1 [nucleoplasm]
(Mus musculus)
Met [nucleoplasm]
(Drosophila melanogaster)
Homologues of ARNTL [nucleoplasm]
(Drosophila melanogaster)
gce [nucleoplasm]
(Drosophila melanogaster)
ARNTL [nucleoplasm]
(Bos taurus)
ARNTL [nucleoplasm]
(Sus scrofa)
BMAL1 [nucleoplasm]
(Canis familiaris)
bmal1 [nucleoplasm]
(Xenopus tropicalis)
bmal1a [nucleoplasm]
(Danio rerio)
Arntl [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
XP_016873236.1
,
XP_016873235.1
,
NP_001284651.1
,
NP_001284648.1
,
NP_001169.3
,
XP_011518415.1
,
XP_016873232.1
,
XP_016873237.1
,
NP_001025444.1
,
NP_001284653.1
,
NP_001025443.1
,
XP_011518414.1
,
XP_016873231.1
OpenTargets
ENSG00000133794
GeneCards
O00327
HPA
ENSG00000133794-BMAL1
Ensembl
ENST00000529388
,
ENSP00000385581
,
ENST00000389707
,
ENSP00000385915
,
ENST00000403290
,
ENSP00000384517
,
ENSP00000374357
,
ENSG00000133794
,
ENST00000403482
,
ENSP00000385897
,
ENST00000403510
,
ENST00000401424
,
ENSP00000433571
PRO
O00327
Pharos - Targets
O00327
PDB
4H10
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15516 CLOCK
3
p-S-CLOCK [nucleoplasm]
(R-HSA-421310)
CLOCK [cytosol]
(R-HSA-400392)
CLOCK [nucleoplasm]
(R-HSA-879828)
0.796
7
UniProt:Q99743 NPAS2
2
NPAS2 [cytosol]
(R-HSA-400314)
p-S-NPAS2 [nucleoplasm]
(R-HSA-421309)
0.632
4
UniProt:D0VY79 D0VY79
0.556
3
UniProt:Q9Y463 DYR1B
0.527
2
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