GFI1 gene expression is enhanced by CEBPA

Stable Identifier
R-HSA-9634446
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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GFI1 gene expression is enhanced by CEBPA
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CEBPA bound to the promoter of the GFI1 gene activates transcription of GFI1 approximately 3-fold (inferred from mouse homologs). Activation of the transcription repressor GFI1 by CEBPA is required for the inhibition of cellular proliferation caused by CEBPA (inferred from mouse homologs).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
GFI1 gene:CEBPA dimer [nucleoplasm] (Homo sapiens)
Inferred From
Gfi1 gene expression is enhanced by Cebpa (Mus musculus)
Authored
May, B  (2018-08-15)
Reviewed
Skokowa, J  (2019-03-10)
Created
May, B  (2019-01-11)
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