Reactome | NUP188 [cytosol]

NUP188 [cytosol]

Stable Identifier

R-HSA-9634172

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Nup188

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5SRE5 NUP188

Gene Names

NUP188, KIAA0169

Chain

initiator methionine:, chain:2-1749

Reference Genes

BioGPS Gene:23511 NUP188

COSMIC (genes):NUP188 NUP188

CTD Gene:23511 NUP188

dbSNP Gene:23511 NUP188

ENSEMBL:ENSG00000095319 NUP188

HGNC:17859 NUP188

KEGG:hsa:23511 NUP188

Monarch:23511 NUP188

NCBI Gene:23511 NUP188

OMIM:615587 NUP188

UCSC:Q5SRE5 NUP188

Reference Transcript

RefSeq:NM_015354.2 NUP188

Other Identifiers

11755763_a_at

17089898

212691_PM_at

212691_at

214675_PM_at

214675_at

217601_PM_at

217601_at

23511

2536484

3190824

3190825

3190826

3190827

3190828

3190829

3190830

3190831

3190832

3190833

3190834

3190836

3190837

3190838

3190839

3190840

3190841

3190842

3190843

3190844

3190845

3190846

3190847

3190848

3190849

3190850

3190851

3190852

3190854

3190855

3190856

3190857

3190858

3190859

3190860

3190861

3190862

3190864

3190865

3190866

3190867

3190868

3190869

3190870

3190871

3190872

3190873

3190874

3190875

3190876

3190877

3190878

3190879

3190880

3190881

3190882

3190883

3190884

32644_at

64338_f_at

7893418

8158446

A_24_P237753

A_24_P273603

D79991_at

GO:0005198

GO:0005634

GO:0005635

GO:0005643

GO:0005829

GO:0006405

GO:0006606

GO:0006886

GO:0006913

GO:0015031

GO:0016020

GO:0017056

GO:0043226

GO:0044611

GO:0051028

HMNXSV003007855

Hs.288146.0.S1_3p_at

Hs.30002.3.S1_3p_at

Hs.30002.5.S1_3p_at

ILMN_1715416

PH_hs_0022534

TC09002285.hg

TC09002909.hg

Participates

as an input of

POM121 and NDC1 bind the Nup93 complex (Homo sapiens)

as a component of

Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] (Homo sapiens)

Other forms of this molecule

NUP188 [nuclear envelope]

Inferred To

nup184 [cytosol] (Schizosaccharomyces pombe)

Nup188 [cytosol] (Drosophila melanogaster)

Nup188 [cytosol] (Mus musculus)

Nup188 [cytosol] (Rattus norvegicus)

NUP188 [cytosol] (Bos taurus)

NUP188 [cytosol] (Canis familiaris)

NUP188 [cytosol] (Gallus gallus)

NUP188 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_056169.1

ENSEMBL

ENST00000372577, ENSP00000361658, ENSG00000095319

OpenTargets

ENSG00000095319

GeneCards

NUP188

HPA

ENSG00000095319-NUP188

PRO

Q5SRE5

Pharos - Targets

Q5SRE5

GlyGen

Q5SRE5

PDB

5IJO, 7R5K, 7R5J

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	13
UniProt:Q80U93	2	Nup214 [nucleoplasm] (R-MMU-451222) Nup214 [cytosol] (R-MMU-157691)	0.564	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4

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