Reactome | ASPH [endoplasmic reticulum lumen]

ASPH [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-9631383

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Aspartyl/asparaginyl beta-hydroxylase, ASPH_HUMAN, junctin

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q12797 ASPH

Gene Names

ASPH, BAH

Chain

chain:1-758

Reference Genes

BioGPS Gene:444 ASPH

COSMIC (genes):ASPH ASPH

CTD Gene:444 ASPH

dbSNP Gene:444 ASPH

ENSEMBL:ENSG00000198363 ASPH

ENSEMBL_homo_sapiens_GENE:ENSG00000198363.18 ASPH

HGNC:757 ASPH

KEGG Gene (Homo sapiens):444 ASPH

Monarch:444 ASPH

NCBI Gene:444 ASPH

OMIM:600582 ASPH

UCSC:Q12797 ASPH

Reference Transcript

Other Identifiers

11721774_a_at

11721775_s_at

11739366_at

11739367_at

11742303_a_at

11747616_a_at

11750180_x_at

11759707_at

205808_PM_at

205808_at

207284_PM_s_at

207284_s_at

209135_PM_at

209135_at

210896_PM_s_at

210896_s_at

224996_PM_at

224996_at

225008_PM_at

225008_at

230429_PM_at

230429_at

3137534

3137535

3137536

3137537

3137538

3137539

3137540

3137541

3137542

3137543

3137550

3137551

3137553

3137558

3137561

3137562

3137565

3137566

3137569

3137574

3137576

3137582

3137584

3137585

3137586

3137587

3137588

3137589

3137596

3137597

3137598

3137600

3137601

3137603

3137605

3137606

3137607

3137610

3137611

3137618

3137619

3137620

3137621

3137622

3137623

3137624

3137625

3137627

3137635

3137636

3137637

3137638

3137639

3137641

3137642

3137643

3137645

3137646

3137653

3137654

3137655

3137656

3137657

37528_at

43336_at

444

56660_at

64711_at

64902_f_at

64903_at

73214_at

8150988

88518_at

A_23_P216094

A_24_P18105

A_24_P295245

GE61576

GE61579

GE63347

GE86882

GO:0003012

GO:0003013

GO:0003824

GO:0005198

GO:0005509

GO:0005513

GO:0005515

GO:0005737

GO:0005783

GO:0005789

GO:0005886

GO:0006091

GO:0006351

GO:0006355

GO:0006886

GO:0006936

GO:0007389

GO:0008283

GO:0008285

GO:0008307

GO:0009055

GO:0010524

GO:0010649

GO:0010880

GO:0010881

GO:0014701

GO:0016020

GO:0016491

GO:0016529

GO:0018193

GO:0022900

GO:0023052

GO:0031585

GO:0031647

GO:0032237

GO:0032541

GO:0033017

GO:0033018

GO:0033198

GO:0034704

GO:0035108

GO:0036211

GO:0042264

GO:0043226

GO:0044325

GO:0045862

GO:0045893

GO:0046872

GO:0048856

GO:0051213

GO:0051604

GO:0055065

GO:0055074

GO:0055085

GO:0060021

GO:0060314

GO:0060316

GO:0060325

GO:0062101

GO:0070588

GO:0071277

GO:0090316

GO:0097202

GO:0140096

GO:1901879

HMNXSV003000148

HMNXSV003005141

HMNXSV003007785

Hs.332422.0.S1_3p_at

Hs.332422.0.S2_3p_at

Hs.55258.0.A1_3p_at

ILMN_1693771

ILMN_1739719

ILMN_2352934

PH_hs_0024953

S83325_s_at

TC08001264.hg

g11878115_3p_at

g11991236_3p_a_at

g4757799_3p_at

g9910363_3p_a_at

Participates

as a component of

ASPH:Fe2+ [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

ASPH [endoplasmic reticulum membrane]

Cross References

RefSeq

NP_004309.2, NP_001158223.1, NP_001158227.1, NP_001158228.1, NP_115856.1, NP_001158222.1, NP_001158225.1, NP_115855.1, NP_064549.1, NP_115857.1

OpenTargets

ENSG00000198363

HPA

ENSG00000198363-ASPH

GeneCards

Q12797

Ensembl

ENSP00000437864, ENSP00000429160, ENSP00000436188, ENST00000517847, ENST00000522835, ENST00000517903, ENSP00000368767, ENST00000541428, ENSP00000394013, ENST00000518068, ENST00000445642, ENSP00000368762, ENST00000522603, ENSP00000373856, ENST00000379449, ENSP00000429286, ENSP00000429954, ENST00000356457, ENSP00000348841, ENSP00000430245, ENSG00000198363, ENST00000389204, ENST00000379454

PRO

Q12797

Pharos - Targets

Q12797

Orphanet

23143

HMDB Protein

HMDBP01022

PDB

5JTC, 6Z6R, 6QA5, 7E6J, 7YB8, 5JZ8, 7YB9, 6RK9, 5JQY, 5JZ6, 6YYY, 6Z6Q, 5APA, 6YYX, 5JZU, 7YBA, 6YYW, 7YBB, 6YYV, 6YYU, 7YBC, 7BMJ, 6Q9I, 5JZA, 6Q9F, 7BMI

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NE86 MCU	1	MCU [mitochondrial inner membrane] (R-HSA-8949184)	0.527	3
UniProt:Q99435 NELL2	1	NELL2 [extracellular region] (R-HSA-9010198)	0.527	2
UniProt:Q9BQ95 ECSIT	2	ECSIT [cytosol] (R-HSA-168064) ECSIT [mitochondrial inner membrane] (R-HSA-5689047)	0.527	3
UniProt:Q9NWR8 MCUB	1	MCUB [mitochondrial inner membrane] (R-HSA-8949153)	0.527	3
UniProt:Q8NC56 LEMD2	1	LEMD2 [nuclear envelope] (R-HSA-3067329)	0.527	3
UniProt:Q9H4I9 SMDT1	3	SMDT1 transit peptide [mitochondrial matrix] (R-HSA-8949642) SMDT1 [mitochondrial inner membrane] (R-HSA-8949227) proSMDT1 [mitochondrial inner membrane] (R-HSA-8949655)	0.527	2
UniProt:O00186 STXBP3	4	p-Y521-STXBP3 [plasma membrane] (R-HSA-2263472) STXBP3 [plasma membrane] (R-HSA-2263473) p-STXBP3 [cytosol] (R-HSA-114680) STXBP3 [cytosol] (R-HSA-114682)	0.527	3
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.527	3
UniProt:P06276 BCHE	2	BCHE [extracellular region] (R-HSA-434469) BCHE [plasma membrane] (R-HSA-3640835)	0.527	2
UniProt:Q12981 BNIP1	1	BNIP1 [endoplasmic reticulum membrane] (R-HSA-6810950)	0.527	2
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.482	2