NEIL1 translocates to the nucleus

Stable Identifier
R-HSA-9629918
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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NEIL1 localizes to the nucleus. The nuclear localization signal (NLS) is predicted to be located at positions 359-378 of NEIL1, but the mechanism of NEIL1 translocation from the cytosol to the nucleus has not been elucidated (Shinmura et al. 2015).

Literature References
PubMed ID Title Journal Year
26095805 NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations

Shinmura, K, Kato, H, Kawanishi, Y, Goto, M, Tao, H, Inoue, Y, Nakamura, S, Sugimura, H

Gene 2015
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