Reactome | NEIL1 translocates to the nucleus

NEIL1 translocates to the nucleus

Stable Identifier

R-HSA-9629918

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

cytosol, nucleoplasm

ReviewStatus

5/5

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NEIL1 localizes to the nucleus. The nuclear localization signal (NLS) is predicted to be located at positions 359-378 of NEIL1, but the mechanism of NEIL1 translocation from the cytosol to the nucleus has not been elucidated (Shinmura et al. 2015).

Literature References

PubMed ID	Title	Journal	Year
26095805	NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations Shinmura, K, Kato, H, Kawanishi, Y, Goto, M, Tao, H, Inoue, Y, Nakamura, S, Sugimura, H	Gene	2015