NEIL3 recognizes and binds to thymine glycol

Stable Identifier
R-HSA-9629369
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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NEIL3 recognizes oxidatively damaged thymine in the form of thymine glycol (Tg) in DNA, with a preference for single strand DNA (ssDNA) over double-strand DNA (dsDNA) (Liu et al. 2012, Zhou et al. 2013).

Literature References
PubMed ID Title Journal Year
22569481 Expression and purification of active mouse and human NEIL3 proteins

Liu, M, Bandaru, V, Holmes, A, Averill, AM, Cannan, W, Wallace, SS

Protein Expr. Purif. 2012
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