NEIL3 recognizes and binds to thymine glycol

Stable Identifier
R-HSA-9629369
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NEIL3 recognizes and binds to thymine glycol
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NEIL3 recognizes oxidatively damaged thymine in the form of thymine glycol (Tg) in DNA, with a preference for single strand DNA (ssDNA) over double-strand DNA (dsDNA) (Liu et al. 2012, Zhou et al. 2013).
Literature References
PubMed ID Title Journal Year
22569481 Expression and purification of active mouse and human NEIL3 proteins

Cannan, W, Holmes, A, Averill, AM, Bandaru, V, Liu, M, Wallace, SS

Protein Expr. Purif. 2012
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Inferred From
Neil3 recognizes and binds to thymine glycol (Mus musculus)
Authored
Orlic-Milacic, M  (2019-01-05)
Reviewed
Zhou, J  (2019-02-11)
Created
Orlic-Milacic, M  (2018-11-21)
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