S100A8:S100A9:AA:Ca2+ [cytosol]

Stable Identifier
R-HSA-9626862
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
calprotectin heterotetramer:AA:Ca2+
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Literature References
PubMed ID Title Journal Year
10976885 Calcium-induced noncovalently linked tetramers of MRP8 and MRP14 are confirmed by electrospray ionization-mass analysis

Strupat, K, Rogniaux, H, Van Dorsselaer, A, Roth, J, Vogl, T

J. Am. Soc. Mass Spectrom. 2000
16690079 Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity

Leukert, N, Vogl, T, Strupat, K, Reichelt, R, Sorg, C, Roth, J

J. Mol. Biol. 2006
17553524 The crystal structure of the human (S100A8/S100A9)2 heterotetramer, calprotectin, illustrates how conformational changes of interacting alpha-helices can determine specific association of two EF-hand proteins

Korndörfer, IP, Brueckner, F, Skerra, A

J. Mol. Biol. 2007
Participants
components
Participates
as an input of
as a component of
Inferred To
S100A8:S100A9:AA:Ca2+ [cytosol] (Bos taurus)
S100A8:S100A9:AA:Ca2+ [cytosol] (Canis familiaris)
S100A8:S100A9:AA:Ca2+ [cytosol] (Danio rerio)
S100A8:S100A9:AA:Ca2+ [cytosol] (Gallus gallus)
S100A8:S100A9:AA:Ca2+ [cytosol] (Mus musculus)
S100A8:S100A9:AA:Ca2+ [cytosol] (Rattus norvegicus)
S100A8:S100A9:AA:Ca2+ [cytosol] (Sus scrofa)
S100A8:S100A9:AA:Ca2+ [cytosol] (Xenopus tropicalis)
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