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EEF1A1 [lysosomal membrane]
Stable Identifier
R-HSA-9626022
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Icon
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Chaperone Mediated Autophagy (Homo sapiens)
EEF1A1 binds GTP (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
EEF1A1:GTP [lysosomal membrane] (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
EEF1A1 dissociates from p-GFAP (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
p-GFAP:EEF1A1 [lysosomal membrane] (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
EEF1A1:GTP translocates from lysosomal membrane to cytosol (Homo sapiens)
EEF1A1:GTP [lysosomal membrane] (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
p-GFAP binds EEF1A1 (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
p-GFAP:EEF1A1 [lysosomal membrane] (Homo sapiens)
EEF1A1 [lysosomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P68104 EEF1A1
Gene Names
EEF1A1, EEF1A, EF1A, LENG7
Chain
initiator methionine:, chain:2-462
Reference Genes
BioGPS Gene:1915 EEF1A1
COSMIC (genes):EEF1A1 EEF1A1
CTD Gene:1915 EEF1A1
dbSNP Gene:1915 EEF1A1
ENSEMBL:ENSG00000156508 EEF1A1
HGNC:3189 EEF1A1
KEGG:hsa:1915 EEF1A1
Monarch:1915 EEF1A1
NCBI Gene:1915 EEF1A1
OMIM:130590 EEF1A1
UCSC:P68104 EEF1A1
Reference Transcript
RefSeq:NM_001402.5 EEF1A1
RefSeq:XM_011535514.2 EEF1A1
Other Identifiers
11736052_at
11736053_x_at
11745648_x_at
11747077_x_at
11749754_a_at
11758011_x_at
11763055_x_at
1288_s_at
17020799
17020802
17124688
1915
204892_PM_x_at
204892_x_at
206559_PM_x_at
206559_x_at
213477_PM_x_at
213477_x_at
213583_PM_x_at
213583_x_at
213614_PM_x_at
213614_x_at
227708_PM_at
227708_at
2348021
2348024
2348025
2348028
2348032
2348034
2373154
2569187
2569193
2708373
2708375
2738235
2738237
2744055
2744059
2778490
2849416
2849418
2849420
2855646
2855648
2855656
2855660
2855664
2855666
2960895
2960897
2960899
2960901
2960902
2960904
2960905
2960906
2960907
2960908
2960909
2960910
2960911
2960912
2960913
2960914
2960915
2960916
2960917
2960918
2960919
2960920
2960921
2960922
2960923
2960924
2960925
2960926
2960927
2960928
2960929
2960930
2960931
2960932
2960933
2960934
2960935
2960936
2960937
2960938
2960939
2960940
2960941
2960942
2960943
2960944
2960945
2960946
2960947
2960948
2960949
3041173
3041175
3041176
3041177
3041178
3041181
3041182
3041183
3041184
3041185
3041186
3041187
3041188
3192641
3192642
3192643
3192644
3192645
3192647
3192648
3192649
3192650
3192651
3192652
3412272
3446487
3466940
3483213
3624916
3830461
40886_at
40887_g_at
57355_f_at
60075_f_at
68493_r_at
8127542
8127544
8138531
8158952
91422_at
A_24_P763243
A_32_P47701
A_33_P3387272
GE79868
GO:0000049
GO:0003723
GO:0003746
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005634
GO:0005730
GO:0005737
GO:0005829
GO:0005840
GO:0005853
GO:0005856
GO:0005886
GO:0006412
GO:0006414
GO:0016020
GO:0016787
GO:0019900
GO:0019901
GO:0022626
GO:0030864
GO:0032587
GO:0034774
GO:0043226
GO:0044829
GO:0045182
GO:0060090
GO:0070062
GO:0071364
GO:0098574
GO:1900022
GO:1904714
GO:1904813
HMNXSV003004771
HMNXSV003036578
Hs.181165.6.A1_3p_at
Hs.284136.2.S1_3p_x_at
ILMN_1343291
ILMN_1810810
ILMN_2038774
J04617_s_at
PH_hs_0030265
TC06001874.hg
TC06001875.hg
TC06003716.hg
TC07002822.hg
TC09002314.hg
X03689_s_at
g4503470_3p_x_at
p14248
Participates
as an input of
EEF1A1 binds GTP (Homo sapiens)
p-GFAP binds EEF1A1 (Homo sapiens)
as a component of
EEF1A1:GTP [lysosomal membrane] (Homo sapiens)
p-GFAP:EEF1A1 [lysosomal membrane] (Homo sapiens)
as an output of
EEF1A1 dissociates from p-GFAP (Homo sapiens)
Other forms of this molecule
EEF1A1 [cytosol]
EEF1A1 [secretory granule lumen]
EEF1A1 [extracellular region]
EEF1A1 [ficolin-1-rich granule lumen]
Me3K318-EEF1A1 [cytosol]
Me3K79-EEF1A1 [cytosol]
Cross References
RefSeq
XP_011533816.1
,
NP_001393.1
OpenTargets
ENSG00000156508
ENSEMBL
ENSP00000503249
,
ENST00000455918
,
ENSP00000479055
,
ENSP00000348651
,
ENST00000615060
,
ENST00000677236
,
ENST00000676710
,
ENST00000309268
,
ENST00000316292
,
ENSP00000339063
,
ENSP00000339053
,
ENST00000678702
,
ENST00000356303
,
ENSP00000503192
,
ENSP00000504335
,
ENSP00000392366
,
ENST00000331523
,
ENST00000678508
,
ENSP00000330054
,
ENSP00000503823
HPA
ENSG00000156508-EEF1A1
ZINC - Substances
EF1A1_HUMAN
ZINC target
P68104
PRO
P68104
Pharos - Targets
P68104
GlyGen
P68104
ZINC - Predictions - Purchasable
EF1A1_HUMAN
HMDB Protein
HMDBP01875
PDB
3C5J
,
8G6J
,
8G60
,
6ZMO
Interactors (32)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14166 TTLL12
1
TTLL12 [cytosol]
(R-HSA-8866300)
0.742
7
UniProt:Q00987 MDM2
11
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
MDM2 [cytosol]
(R-HSA-198644)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
MDM2 [plasma membrane]
(R-HSA-416843)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
monoSUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
0.709
9
UniProt:P26641 EEF1G
3
EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol]
(R-HSA-9710850)
EEF1G(1-343)-ALK(1106-1620) fusion [cytosol]
(R-HSA-9710839)
EEF1G [cytosol]
(R-HSA-156925)
0.643
5
UniProt:Q05516 ZBTB16
1
ZBTB16 [cytosol]
(R-HSA-976047)
0.593
4
UniProt:P12004 PCNA
5
PCNA [nucleoplasm]
(R-HSA-68439)
MonoUb-K164-PCNA [nucleoplasm]
(R-HSA-5651986)
ISG-K164,ISG-K168-PCNA [nucleoplasm]
(R-HSA-5653768)
K63polyUb-K164-PCNA [nucleoplasm]
(R-HSA-8943000)
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
(R-HSA-4615861)
0.573
2
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
8
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.564
2
UniProt:Q96IK1-2 Q96IK12
0.556
3
UniProt:O43504 LAMTOR5
1
LAMTOR5 [lysosomal membrane]
(R-HSA-5655441)
0.553
2
UniProt:O95257 GA45G
0.553
2
UniProt:Q16539 MAPK14
7
MAPK14 [ficolin-1-rich granule lumen]
(R-HSA-6803280)
MAPK14 [extracellular region]
(R-HSA-6806453)
MAPK14 [secretory granule lumen]
(R-HSA-6803300)
MAPK14 [nucleoplasm]
(R-HSA-446223)
MAPK14 [cytosol]
(R-HSA-428933)
p-T180,Y182-MAPK14 [cytosol]
(R-HSA-428935)
p-T180,Y182-MAPK14 [nucleoplasm]
(R-HSA-446227)
0.547
3
UniProt:Q9Y6G3 MRPL42
1
MRPL42 [mitochondrial inner membrane]
(R-HSA-5368237)
0.547
2
UniProt:Q9NYA1 SPHK1
4
SPHK1 [nucleoplasm]
(R-HSA-9836616)
p-S225-SPHK1 [nucleoplasm]
(R-HSA-9836613)
p-S225-SPHK1 [cytosol]
(R-HSA-5218716)
SPHK1 [cytosol]
(R-HSA-391267)
0.544
2
UniProt:Q9NZ94-2 NLGN3
0.543
4
UniProt:Q9BVG4 PBDC1
0.527
4
UniProt:Q15843 NEDD8
8
C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm]
(R-HSA-8952504)
NEDD8 [nucleoplasm]
(R-HSA-8955926)
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(R-HSA-4419895)
NEDD8 [cytosol]
(R-HSA-416969)
C237-UBA3-G76-NEDD8 [cytosol]
(R-HSA-8951647)
NEDD8(1-81) [cytosol]
(R-HSA-5690794)
NEDD8(77-81) [cytosol]
(R-HSA-6782654)
C116-AcM-UBE2F-G76-NEDD8 [cytosol]
(R-HSA-8951739)
0.527
2
UniProt:Q8WVE0 N6AMT2
1
N6AMT2 [cytosol]
(R-HSA-1183209)
0.527
2
UniProt:P43355 MAGA1
0.527
3
UniProt:P24534 EEF1B2
1
EEF1B2 [cytosol]
(R-HSA-156926)
0.527
4
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.527
2
UniProt:Q77M19 Q77M19
0.527
2
UniProt:P26640 VARS1
1
VARS [cytosol]
(R-HSA-379648)
0.527
4
UniProt:O75312 ZPR1
0.527
3
UniProt:P67775 PPP2CA
4
PPP2CA [cytosol]
(R-HSA-165971)
PPP2CA [nucleoplasm]
(R-HSA-165978)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
0.527
3
UniProt:Q05639 EEF1A2
1
EEF1A2 [cytosol]
(R-HSA-3907261)
0.527
5
UniProt:Q14192 FHL2
1
FHL2 [nucleoplasm]
(R-HSA-561161)
0.527
3
UniProt:Q8NFJ9 BBS1
1
BBS1 [cytosol]
(R-HSA-5617640)
0.508
3
UniProt:Q8IUH5 ZDH17
0.508
2
UniProt:P06788 VE7
0.488
2
UniProt:P24837 VE7
0.488
2
UniProt:P36827 VE7
0.488
2
UniProt:P03129 VE7
0.488
2
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