ABCA6 gene expression is stimulated by FOXO1,FOXO3

Stable Identifier
R-HSA-9625092
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, plasma membrane
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ABCA6 gene expression is stimulated by FOXO1,FOXO3
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FOXO1 and FOXO3 directly stimulate transcription of the ABCA6 (ATP-binding cassette sub-family A member 6) gene, encoding a putative transporter protein responsive to cholesterol and thought to be involved in lipid homeostasis (Gai et al. 2013).

Literature References
PubMed ID Title Journal Year
24028821 FoxO regulates expression of ABCA6, an intracellular ATP-binding-cassette transporter responsive to cholesterol

Ji, M, Shi, C, Li, W, Chen, S, Gai, J, Li, H, Wang, Y

Int. J. Biochem. Cell Biol. 2013
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
FOXO1,FOXO3:ABCA6 gene [nucleoplasm] (Homo sapiens)
Active Unit
FOXO1,FOXO3 [nucleoplasm]
Authored
Orlic-Milacic, M  (2018-10-23)
Reviewed
Donlon, T  (2018-10-23)
Created
Orlic-Milacic, M  (2018-10-18)
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