FOXO1,FOXO3 binds CAV1 gene promoter

Stable Identifier
R-HSA-9624976
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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FOXO3 binds the promoter of the CAV1 gene, encoding Caveolin-1 (van den Heuvel et al. 2005, Nho et al. 2013, Sisci et al. 2013). FOXO1 also binds the CAV1 gene promoter (Roy et al. 2008).

Literature References
PubMed ID Title Journal Year
24047697 The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness

Ferraro, A, Cesario, MG, Coroniti, R, Maris, P, Romeo, F, Sisci, D, Mauro, L, Trombino, GE, Morelli, C, Aquila, S, Andó, S, Maggiolini, M, Lanzino, M, Anselmo, W

Cell Cycle 2013
18444242 Wild-type APC regulates caveolin-1 expression in human colon adenocarcinoma cell lines via FOXO1a and C-myc

Ignatenko, NA, Gerner, EW, Fultz, KE, Henkhaus, RS, Mora, J, Roy, UK

Mol. Carcinog. 2008
23580232 FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas

Peterson, M, Henke, CA, Nho, RS, Hergert, P

PLoS ONE 2013
15458387 Direct control of caveolin-1 expression by FOXO transcription factors

Burgering, BM, Schulze, A, van den Heuvel, AP

Biochem. J. 2005
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