CDK1 phosphorylates LBR

Stable Identifier
R-HSA-9624800
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nuclear envelope
ReviewStatus
5/5
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CDK1 phosphorylates LBR
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During mitosis, CDK1 phosphorylates LBR (lamin B receptor) on N-terminal serine residues S71 and S86. S71 is the major CDK1 phosphorylation site in LBR (Tseng and Chen 2011).
Literature References
PubMed ID Title Journal Year
21795390 Temporal control of nuclear envelope assembly by phosphorylation of lamin B receptor

Tseng, LC, Chen, RH

Mol. Biol. Cell 2011
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Output
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as an event of
Catalyst Activity

cyclin-dependent protein serine/threonine kinase activity of CCNB1,CCNB2:p-T161-CDK1 [cytosol]

Physical Entity
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Homo sapiens)
Activity
cyclin-dependent protein serine/threonine kinase activity (GO:0004693)
Orthologous Events
CDK1 phosphorylates LBR (Bos taurus)
CDK1 phosphorylates LBR (Canis familiaris)
CDK1 phosphorylates LBR (Danio rerio)
CDK1 phosphorylates LBR (Gallus gallus)
CDK1 phosphorylates LBR (Mus musculus)
CDK1 phosphorylates LBR (Rattus norvegicus)
CDK1 phosphorylates LBR (Sus scrofa)
CDK1 phosphorylates LBR (Xenopus tropicalis)
Authored
Gerace, L  (2019-11-07)
Created
Orlic-Milacic, M  (2018-10-15)
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