CEBPA interacts with CDKN1A (p21), resulting in a cooperative inhibition of CDK2 and cellular proliferation (Harris et al. 2001). CEBPA also increases the cellular abundance of CDKN1A by stabilizing the CDKN1A protein and activating transcription of the CDKN1A gene (Timchenko et al. 1996, Quintana-Bustamante et al. 2012).
Lan-Lan Smith, S,