FOXO1 binds PPARGC1A

Stable Identifier
R-HSA-9623240
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Based on experiments in a mouse model system, FOXO1 forms a complex with the transcriptional co-activator PPARGC1A (PGC-1alpha). The interaction between FOXO1 and PPARGC1A is disrupted by AKT-mediated phosphorylation of FOXO1 (Puigserver et al. 2003).

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