FOXO1 binds POMC gene promoter

Stable Identifier
R-HSA-9623059
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Based on studies in mice, FOXO1 binds the promoter of the POMC gene, encoding Pro-opiomelanocortin (Kitamura et al. 2006). FOXO1-mediated repression of the POMC gene is positively regulated by SIRT1-mediated deacetylation of FOXO1 (Cakir et al. 2009).

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