CAMK1 phosphorylates ARHGEF7-1

Stable Identifier
R-HSA-9619783
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
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CAMK1 phosphorylates ARHGEF7-1
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At dendritic spines, CAMK1, activated by CaMKK-mediated phosphorylation downstream of NMDA receptor activation, phosphorylates GIT1-bound ARHGEF7 (beta-PIX) on serine residue S516 (Saneyoshi et al. 2013).

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Output
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as an event of
Catalyst Activity

calmodulin-dependent protein kinase activity of p-T177-CAMK1:CALM1:4xCa2+ [cytosol]

Physical Entity
p-T177-CAMK1:CALM1:4xCa2+ [cytosol] (Homo sapiens)
Activity
calmodulin-dependent protein kinase activity (GO:0004683)
Inferred From
Camk1 phosphorylates Arhgef7 (Rattus norvegicus)
Authored
Orlic-Milacic, M  (2018-10-10)
Reviewed
Hansen, KB  (2018-11-02)
Yi, F  (2018-11-02)
Created
Orlic-Milacic, M  (2018-09-18)
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