AMPK negatively regulates binding of MAPT to microtubules

Stable Identifier
R-HSA-9619542
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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AMPK negatively regulates binding of MAPT to microtubules
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AMPK-mediated phosphorylation of MAPT (Tau) interferes with binding of MAPT to the microtubules (Thornton et al. 2011).

Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
p-AMPK heterotrimer [cytosol] (Homo sapiens)
Inferred From
AMPK-negatively regulates binding of MAPT to microtubules (Bos taurus)
Authored
Orlic-Milacic, M  (2018-10-10)
Reviewed
Hansen, KB  (2018-11-02)
Yi, F  (2018-11-02)
Created
Orlic-Milacic, M  (2018-09-18)
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