CaMKKs phosphorylate CAMK1

Stable Identifier
R-HSA-9619367
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
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CaMKKs phosphorylate CAMK1
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Both CaMKKs, CAMKK1 (Haribabu et al. 1995) and CAMKK2 (Woods et al. 2005), phosphorylate CAMK1 on threonine residue T177 in a calmodulin-dependent manner.

Participants
Input
Output
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as an event of
Catalyst Activity

calmodulin-dependent protein kinase activity of p-CaMKK:CALM1:4xCa2+ [cytosol]

Physical Entity
p-CaMKK:CALM1:4xCa2+ [cytosol] (Homo sapiens)
Activity
calmodulin-dependent protein kinase activity (GO:0004683)
Inferred From
CAMKK2 phosphorylates Camk1 (Homo sapiens)
CAMKK1 phosphorylates CAMK1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-10)
Reviewed
Hansen, KB  (2018-11-02)
Yi, F  (2018-11-02)
Created
Orlic-Milacic, M  (2018-09-14)
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