EP300,CREBBP bind SOH-C481-FOXO4

Stable Identifier
R-HSA-9617683
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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EP300,CREBBP bind SOH-C481-FOXO4
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After oxidation of FOXO4 cysteine residues by reactive oxygen species (ROS), FOXO4 forms a complex with a protein acetyltransferase EP300 (p300) or CREBBP (CBP). A covalent disulfide bond between FOXO4 and EP300 or CREBBP facilitates complex formation (Dansen et al. 2009).
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Inferred From
Crebbp binds SOH-C477-Foxo4 (Mus musculus)
EP300 binds SOH-C477-Foxo4 (Mus musculus)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-08-30)
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