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p-T286-CaMKII dodecamer [cytosol]
Stable Identifier
R-HSA-9617584
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-T286-CAMK2 dodecamer
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Oncogenic MAPK signaling (Homo sapiens)
Paradoxical activation of RAF signaling by kinase inactive BRAF (Homo sapiens)
RAF is paradoxically phosphorylated downstream of kinase-inactive RAF (Homo sapiens)
RAF activating kinases [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Signaling by BRAF and RAF1 fusions (Homo sapiens)
BRAF and RAF fusion mutant dimers are phosphorylated (Homo sapiens)
RAF activating kinases [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Signaling by RAF1 mutants (Homo sapiens)
Phosphorylation of RAF1 mutants (Homo sapiens)
RAF activating kinases [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Signaling by RAS mutants (Homo sapiens)
Signaling downstream of RAS mutants (Homo sapiens)
RAF is phosphorylated downstream of oncogenic RAS (Homo sapiens)
RAF activating kinases [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Signaling by moderate kinase activity BRAF mutants (Homo sapiens)
RAF is phosphorylated downstream of moderate kinase activity BRAF mutants (Homo sapiens)
RAF activating kinases [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Negative regulation of NMDA receptor-mediated neuronal transmission (Homo sapiens)
PPM1F dephosphorylates p-T286-CaMKII (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
Long-term potentiation (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
CaMKII binds activated NMDA receptor (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
CaMKII phosphorylates AMPA receptor (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAF activation (Homo sapiens)
Phosphorylation of RAF (Homo sapiens)
RAF activating kinases [plasma membrane] (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
p-T286-CaMKII dodecamer [cytosol] (Homo sapiens)
General
CaMKII is composed of a homo or hetero dodecamer of four subunits apha, beta, delta and gamma. In a heteromultimer the ratio of alpha to beta may vary from 6;1, 3:1 or 1:1.
Participants
components
x 12
p-T286-CAMK2A,p-T287-CAMK2B,(p-T287-CAMK2D,p-T287-CAMK2G) [cytosol]
(Homo sapiens)
Participates
as a component of
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
Inferred To
p-T286-CaMKII dodecamer [cytosol]
(Bos taurus)
p-T286-CaMKII dodecamer [cytosol]
(Caenorhabditis elegans)
p-T286-CaMKII dodecamer [cytosol]
(Canis familiaris)
p-T286-CaMKII dodecamer [cytosol]
(Drosophila melanogaster)
p-T286-CaMKII dodecamer [cytosol]
(Gallus gallus)
p-T286-CaMKII dodecamer [cytosol]
(Mus musculus)
p-T286-CaMKII dodecamer [cytosol]
(Rattus norvegicus)
p-T286-CaMKII dodecamer [cytosol]
(Sus scrofa)
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