CEBPA binds the promoter of the CEBPE gene

Stable Identifier
R-HSA-9616241
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CEBPA binds the promoter of the CEBPE gene
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CEBPA homodimers bind the promoter of the CEBPE gene (Loke et al. 2018 and inferred from mouse homologs). It is unclear if CEBPA homodimerizes before or during binding to DNA.

Literature References
PubMed ID Title Journal Year
29431622 C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia

Pickin, A, Imperato, MR, Bonifer, C, Ptasinska, A, Cockerill, PN, Loke, J, Keane, P, Assi, SA, Chin, PS

Blood Adv 2018
Participants
Input
Output
Participates
as an event of
Inferred From
Cebpa binds the promoter of the Cebpe gene (Mus musculus)
Authored
May, B  (2018-08-10)
Reviewed
Skokowa, J  (2019-03-10)
Created
May, B  (2018-08-10)
Cite Us!