14-3-3 proteins bind AKT-phosphorylated FOXO4

Stable Identifier
Reaction [binding]
Homo sapiens
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Nuclear exclusion and cytoplasmic retention of AKT-phosphorylated FOXO4 is promoted by binding of FOXO4 to 14-3-3 zeta (YWHAZ) (Obsilova et al. 2005, Boura et al. 2007, Silhan et al. 2009).

Literature References
PubMed ID Title Journal Year
19416966 14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4

Sulc, M, Silhan, J, Obsil, T, Obsilova, V, Vecer, J, Strnadova, P, Teisinger, J, Herman, P, Vacha, P

J. Biol. Chem. 2009
17244620 Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding

Sulc, M, Silhan, J, Boura, E, Obsil, T, Obsilova, V, Vecer, J, Teisinger, J, Herman, P

J. Biol. Chem. 2007
16114898 14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4

Sulc, M, Boura, E, Obsil, T, Obsilova, V, Pabianova, A, Vecer, J, Teisinger, J, Herman, P

Biochemistry 2005
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