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HCMV Nuclear Pore Docking
Stable Identifier
R-HSA-9614367
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human cytomegalovirus
Compartment
nuclear envelope
ReviewStatus
5/5
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HCMV Infection (Homo sapiens)
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HCMV Nuclear Pore Docking (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Virion capsids eventually dissociate from microtubules, dock at nuclear pores, and release their DNA into the nucleus. The role of tegument proteins in this process is implicated but has not been described in detail.
Literature References
PubMed ID
Title
Journal
Year
18535146
Tegument proteins of human cytomegalovirus
Kalejta, RF
Microbiol. Mol. Biol. Rev.
2008
Participants
Input
HCMV Tegmented Capsid:Dynein:Microtubule [cytoplasm]
(Homo sapiens)
Nuclear Pore Complex (NPC) [nuclear envelope]
(Homo sapiens)
Output
Dynein complex [cytosol]
(Homo sapiens)
HCMV Capsid:Nuclear Pore Complex [nuclear envelope]
(Homo sapiens)
HCMV Tegument Proteins [viral tegument]
(Human cytomegalovirus)
Microtubule [cytosol]
(Homo sapiens)
Participates
as an event of
HCMV Early Events (Homo sapiens)
Disease
Name
Identifier
Synonyms
viral infectious disease
DOID:934
Viral disease, virus infection, virus infection
Reviewed
Streblow, DN (2019-10-18)
Caposio, P (2019-10-18)
Created
Gillespie, ME (2018-07-25)
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