ERBB4s80 binds ADAP1 gene

Stable Identifier
R-HSA-9612255
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
ERBB4s80 binds ADAP1 gene
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The intracellular fragment of ERBB4, ERBB4s80 (E4ICD) binds to the promoter region of the ADAP1 gene, about 3-4 kb upstream of the transcription start site. The ERBB4s80 binding site overlaps with a CEBPB binding site (Wali et al. 2014).

Literature References
PubMed ID Title Journal Year
24829397 Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells

Wali, VB, Haskins, JW, Gilmore-Hebert, M, Platt, JT, Liu, Z, Stern, DF

Mol. Cancer Res. 2014
Participants
Input
Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2018-06-28)
Stern, DF  (2019-02-21)
Created
Orlic-Milacic, M  (2018-06-27)