The intracellular fragment of ERBB4, ERBB4s80 (E4ICD) binds to the promoter region of the APOE gene, about 2 kb upstream from the transcription start site. The ERBB4s80 binding site overlaps with HNF4 and ETS1 binding sites (Wali et al. 2014).
Liu, Z, Gilmore-Hebert, M, Stern, DF, Wali, VB, Platt, JT, Haskins, JW
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