ERBB4s80 binds the APOE gene

Stable Identifier
R-HSA-9612246
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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ERBB4s80 binds the APOE gene
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The intracellular fragment of ERBB4, ERBB4s80 (E4ICD) binds to the promoter region of the APOE gene, about 2 kb upstream from the transcription start site. The ERBB4s80 binding site overlaps with HNF4 and ETS1 binding sites (Wali et al. 2014).

Literature References
PubMed ID Title Journal Year
24829397 Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells

Wali, VB, Haskins, JW, Gilmore-Hebert, M, Platt, JT, Liu, Z, Stern, DF

Mol. Cancer Res. 2014
Participants
Input
Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2018-06-28)
Stern, DF  (2019-02-21)
Created
Orlic-Milacic, M  (2018-06-27)