The intracellular fragment of ERBB4, ERBB4s80 (E4ICD) binds to the promoter region of the APOE gene, about 2 kb upstream from the transcription start site. The ERBB4s80 binding site overlaps with HNF4 and ETS1 binding sites (Wali et al. 2014).
Wali, VB, Haskins, JW, Gilmore-Hebert, M, Platt, JT, Liu, Z, Stern, DF
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