Endocytic Uptake of HCMV Virion

Stable Identifier
R-HSA-9611147
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human cytomegalovirus
Compartment
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Once the pentameric viral protein complex, gH:gL:p128:p130:p131A, facilitates attchment of the Human Cytomegalovirus (HCMV) endocytic uptake allows the virion to enter epithelial and endothelial cells. The virion is released from the endocytic vesicle by low-pH-dependent fusion of the virion coat with endosomes membrane.

Literature References
PubMed ID Title Journal Year
  Fields Virology

Knipe, DM, Howley, PM

  2013
Participants
Participant Of
Event Information
Go Biological Process
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