Endocytic Uptake of HCMV Virion

Stable Identifier
R-HSA-9611147
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human cytomegalovirus
Compartment
plasma membrane
ReviewStatus
5/5
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Endocytic Uptake of HCMV Virion
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Once the pentameric viral protein complex, gH:gL:p128:p130:p131A, facilitates attchment of the Human Cytomegalovirus (HCMV) endocytic uptake allows the virion to enter epithelial and endothelial cells. The virion is released from the endocytic vesicle by low-pH-dependent fusion of the virion coat with endosomes membrane.

Literature References
PubMed ID Title Journal Year
  Fields Virology

Knipe, DM, Howley, PM

  2013
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
viral entry into host cell (0046718)
Disease
Name Identifier Synonyms
viral infectious disease DOID:934 Viral disease, virus infection, virus infection
Authored
Gillespie, ME  (2018-06-14)
Reviewed
Streblow, DN  (2019-10-18)
Caposio, P  (2019-10-18)
Created
Gillespie, ME  (2018-06-15)
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