HCMV Formation of Final Envelopment Complex

Stable Identifier
R-HSA-9610942
Type
Reaction
Species
Homo sapiens
Related Species
Human cytomegalovirus
Compartment
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VPS4A and CHMP1A components localize within the assembly compartment (AC), with a striking colocalization of the chromatin modifying protein 1A (CHMP1A) and assembled gM:gN. Both the Vps4A and CHMP1A localized in the vicinity of viral cytoplasmic assembly compartments are sites of viral maturation that develop in human cytomeglovirus (HCMV)-infected cells. The accumulation of viral tegument also occurs during this step of viral maturation.

Literature References
PubMed ID Title Journal Year
  Fields Virology

Knipe, DM, Howley, PM

  2013
19640981 Human cytomegalovirus exploits ESCRT machinery in the process of virion maturation

Tandon, R, AuCoin, DP, Mocarski, ES

J. Virol. 2009
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Event Information
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This event is regulated
Disease
Name Identifier Synonyms
viral infectious disease 934 arbovirus infectious disease, Viral disease, Viral infection NOS, Viral infection, unspecified (disorder), Viral infection NOS, Viral disease (disorder), Viral disease, Viral infection NOS (disorder), Viral Infection, virus infection, virus infection, Viral: [infection NOS] or [illness]
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